Evidence map›Paper›PMID 30220553›Full record

ArticleThe American journal of pathology2018

Atypical Protein Kinase C: Breaking Down Barriers in Ocular Disease?

Elizabeth A Pearsall, Kip M Connor

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Elizabeth A PearsallAngiogenesis Laboratory, Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts. Electronic address: elizabeth_moran@meei.harvard.edu.
Kip M ConnorAngiogenesis Laboratory, Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts.

Funding

The Alternative Complement System Facilitates Photoreceptor Degeneration in Retinal Detachment.R01EY027303 · NEI · MASSACHUSETTS EYE AND EAR INFIRMARY · PI CONNOR, KIP M · 2018 to 2020
$1.3M
NEI NIH HHS R01 EY027303
6 · The paper itself

Abstract

This commentary highlights the article by Lin et al that demonstrates the therapeutic potential of small-molecule atypical protein kinase C inhibitors in inflammatory ocular disease.

Indexed as

Capillary PermeabilityEye DiseasesHumansInflammationProtein Kinase CPKC-3 proteinProtein Kinase C

Identifiers

PMID30220553
PMCPMC6180271

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.