Evidence map›Paper›PMID 30220413›Full record

ArticleBiophysical journal2018

Ryanodine Receptor Open Times Are Determined in the Closed State.

Michael Fill, Dirk Gillespie

Open access · bronzeAbstract readLetter
In one paragraph

Article in Biophysical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. CaJournal of molecular and cellular cardiology · 2023
    Article
  3. Mechanisms of spontaneous CaThe Journal of physiology · 2023
    Article
  4. Article
  5. The Role of CaBiomolecules · 2022
    Article
  6. Review
  7. Article
  8. Simulating cardiac CaPflugers Archiv : European journal of physiology · 2021
    Article
  9. Recruiting RyRs to Open in a CaBiophysical journal · 2020
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Michael FillDepartment of Physiology and Biophysics, Rush University Medical Center, Chicago, Illinois.
Dirk GillespieDepartment of Physiology and Biophysics, Rush University Medical Center, Chicago, Illinois. Electronic address: dirk_gillespie@rush.edu.
Rush University Medical Center · US

Funding

Limiting Pathological Calcium Induced Calcium Release in HeartR01HL057832 · NHLBI · RUSH UNIVERSITY MEDICAL CENTER · PI FILL, MICHAEL, GILLESPIE, DIRK · 1997 to 2024
$9.0M
Skeletal Muscle Ryanodine Receptor Permeation and Self Counter-Ion FlowR01AR054098 · NIAMS · RUSH UNIVERSITY MEDICAL CENTER · PI FILL, MICHAEL · 2007 to 2017
$2.9M
NHLBI NIH HHS R01 HL057832NIAMS NIH HHS R01 AR054098
6 · The paper itself

Abstract

The ryanodine receptor (RyR) ion channel releases Ca

Indexed as

Ion Channel GatingCalciumCytosolKineticsProbabilityProtein BindingRyanodine Receptor Calcium Release ChannelCalciumRyanodine Receptor Calcium Release Channel

Identifiers

PMID30220413
PMCPMC6170654
OpenAlexW2891199305

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.