Evidence map›Paper›PMID 30220255›Full record

ArticleBMC medicine2018

Impact of preventive primary care on children's unplanned hospital admissions: a population-based birth cohort study of UK children 2000-2013.

Elizabeth Cecil, Alex Bottle, Richard Ma, Dougal S Hargreaves, Ingrid Wolfe, Arch G Mainous, Sonia Saxena

Abstract read
In one paragraph

Article in BMC medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Impact of vaccination on pertussis-related hospital admissions in children in Scotland from January 2013 to July 2024: a cohort study.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Ethnic inequities in 6-8 week baby check coverage in England 2006- 2021: a cohort study using the Clinical Practice Research Datalink.The British journal of general practice : the journal of the Royal College of General Practitioners · 2024
    Article
  9. Article
  10. Observational
  11. Article
  12. Article
  13. Article
  14. Impact of COVID-19 on primary care contacts with children and young people in England: longitudinal trends study 2015-2020.The British journal of general practice : the journal of the Royal College of General Practitioners · 2022
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elizabeth CecilDepartment of Primary Care and Public Health, Imperial College London Charing Cross Campus, London, W6 8RP, UK. e.cecil@imperial.ac.uk.
Alex BottleDepartment of Primary Care and Public Health, Imperial College London Charing Cross Campus, London, W6 8RP, UK.
Richard MaDepartment of Primary Care and Public Health, Imperial College London Charing Cross Campus, London, W6 8RP, UK.
Dougal S HargreavesInstitute of Child Health, University College London, London, England.
Ingrid WolfeDepartment of Primary Care and Public Health Sciences, King's College London, London, England.
Arch G MainousDepartment of Health Services Research, Management and Policy, University of Florida, Gainesville, FL, USA.
Sonia SaxenaDepartment of Primary Care and Public Health, Imperial College London Charing Cross Campus, London, W6 8RP, UK.

Funding

Department of Health CDF-2011-04-048Department of Health DRF-2017-10-181
6 · The paper itself

Abstract

backgroundUniversal health coverage (UHC) aims to improve child health through preventive primary care and vaccine coverage. Yet, in many developed countries with UHC, unplanned and ambulatory care sensitive (ACS) hospital admissions in childhood continue to rise. We investigated the relation between preventive primary care and risk of unplanned and ACS admission in children in a high-income country with UHC.

methodsWe followed 319,780 children registered from birth with 363 English practices in Clinical Practice Research Datalink linked to Hospital Episodes Statistics, born between January 2000 and March 2013. We used Cox regression estimating adjusted hazard ratios (HR) to examine subsequent risk of unplanned and ACS hospital admissions in children who received preventive primary care (development checks and vaccinations), compared with those who did not.

resultsOverall, 98% of children had complete vaccinations and 87% had development checks. Unplanned admission rates were 259, 105 and 42 per 1000 child-years in infants (aged < 1 year), preschool (1-4 years) and primary school (5-9 years) children, respectively. Lack of preventive care was associated with more unplanned admissions. Infants with incomplete vaccination had increased risk for all unplanned admissions (HR 1.89, 1.79-2.00) and vaccine-preventable admissions (HR 4.41, 2.59-7.49). Infants lacking development checks had higher risk for unplanned admission (HR 4.63, 4.55-4.71). These associations persisted across childhood. Children who had higher consulting rates with primary care providers also had higher risk of unplanned admission (preschool children: HR 1.17, 1.17-1.17). One third of all unplanned admissions (62,154/183,530) were for ACS infectious illness. Children with chronic ACS conditions, asthma, diabetes or epilepsy had increased risk of unplanned admission (HR 1.90, 1.77-2.04, HR 11.43, 8.48-15.39, and HR 4.82, 3.93-5.91, respectively). These associations were modified in children who consulted more in primary care.

conclusionsA high uptake of preventive primary care from birth is associated with fewer unplanned and ACS admissions in children. However, the clustering of poor health, a lack of preventive care uptake, and social deprivation puts some children with comorbid conditions at very high risk of admission. Strengthening immunisation coverage and preventive primary care in countries with poor UHC could potentially significantly reduce the health burden from hospital admission in children.

Indexed as

ChildChild, PreschoolCohort StudiesFemaleHospitalizationHospitals, PediatricHumansInfantMalePrimary Health CarePrimary PreventionUnited KingdomUniversal Health InsuranceAmbulatory care sensitive conditionsChild healthPreventive primary careUniversal health coverageUnplanned hospital admissions

Identifiers

PMID30220255
PMCPMC6139908

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.