ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2018
Promoter variations in a homeobox gene, BnA10.LMI1, determine lobed leaves in rapeseed (Brassica napus L.).
Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 62 citations in OpenAlex.
- Machine learning-guided leaf margin classification and discovery that BcPHB promoter selection rewires a BcPHB-BcLMI1 module to shape leaf margins in Brassica campestris.Molecular horticulture · 2026Article
- The HD-ZIP I transcription factor BcLMI1 regulates bolting time inHorticulture research · 2026Article
- Cloning and functional analysis of the lobed-leaf gene BjA10.LL in Brassica juncea L.Stress biology · 2026Article
- RsRCO and RsLMI1 co-regulate the formation of lobed leaf in radish (Raphanus sativus L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Fine mapping of the dominant female sterility gene and novel model of hybrid seed production in cabbage (Brassica oleracea L. var. capitata).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Linkage map construction and QTL mapping for morphological traits in Ipomoea trifida, a diploid sweetpotato relative.The plant genome · 2025Article
- Homeodomain leucine zipper protein controls the lobed leaf formation by modulating auxin distribution in watermelon.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Unlocking genetic potential: a review of the role of CRISPR/Cas technologies in rapeseed improvement.Stress biology · 2025Review
- Article
- Structure and evolution of the Forsythieae genome elucidated by chromosome-level genome comparison of Abeliophyllum distichum and Forsythia ovata (Oleaceae).Communications biology · 2025Article
- A complex locus regulates highly lobed-leaf formation in Brassica juncea.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
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- Promoter variations in a homeobox gene, BrLMI1, contribute to leaf lobe formation in Brassica rapa ssp. chinensis Makino.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Effect of structural variation in the promoter region ofFrontiers in plant science · 2023Article
- Targeted genome editing in polyploids: lessons fromFrontiers in plant science · 2023Review
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- Integrated Analysis of Transcriptome and Metabolome Reveals New Insights into the Formation of Purple Leaf Veins and Leaf Edge Cracks inPlants (Basel, Switzerland) · 2022Article
- The application of CRISPR/Cas technologies toaBIOTECH · 2022Review
- Promoter variation in a homeobox gene, CpDll, is associated with deeply lobed leaf in Cucurbita pepo L.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- Site-Directed Mutagenesis of the Carotenoid Isomerase GeneFrontiers in plant science · 2022Article
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Authors and funding
9 authors at 1 institution in 1 country.
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Abstract
key messageBnA10.LMI1 positively regulates the development of leaf lobes in Brassica napus, and cis-regulatory divergences cause the different allele effects. Leaf shape is an important agronomic trait, and large variations in this trait exist within the Brassica germplasm. The lobed leaf is a unique morphological characteristic for Brassica improvement. Nevertheless, the molecular basis of leaf lobing in Brassica is poorly understood. Here, we show that an incompletely dominant locus, BnLLA10, is responsible for the lobed-leaf shape in rapeseed. A LATE MERISTEM IDENTITY1 (LMI1)-like gene (BnA10.LMI1) encoding an HD-Zip I transcription factor is the causal gene underlying the BnLLA10 locus. Sequence analysis of parental alleles revealed no sequence variations in the coding sequences, whereas abundant variations were identified in the regulatory region. Consistent with this finding, the expression levels of BnLMI1 were substantially elevated in the lobed-leaf parent compared with its near-isogenic line. The knockout mutations of BnA10.LMI1 gene were induced using the CRISPR/Cas9 system in both HY (the lobed-leaf parent) and J9707 (serrated leaf) genetic backgrounds. BnA10.LMI1 null mutations in the HY background were sufficient to produce unlobed leaves, whereas null mutations in the J9707 background showed no obvious changes in leaf shape compared with the control. Collectively, our results indicate that BnA10.LMI1 positively regulates the development of leaf lobes in B. napus, with cis-regulatory divergences causing the different allelic effects, providing new insights into the molecular mechanism of leaf lobe formation in Brassica crops.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.