ArticlePediatric nephrology (Berlin, Germany)2019
Prevalence of risk factors for chronic kidney disease in South African youth with perinatally acquired HIV.
Article in Pediatric nephrology (Berlin, Germany), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Prevalence of chronic kidney disease among young people living with HIV in Sub Saharan Africa: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Kidney Disease in HIV Infected Children on HAART in Nigeria.African health sciences · 2025Article
- Comparison of the prevalence and associated factors of chronic kidney disease diagnosed by serum creatinine or cystatin C among young people living with HIV in Uganda.BMC nephrology · 2024Article
- Comparison of the prevalence and associated factors of chronic kidney disease diagnosed by serum creatinine or cystatin C among young people living with HIV in Uganda.medRxiv : the preprint server for health sciences · 2024Article
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- Microalbuminuria in Perinatally HIV-Infected Children and Adolescents in the United States.Open forum infectious diseases · 2023Article
- Renal Impairment Impact and Survival Analysis in a Romanian Cohort of HIV-1(F1)-Infected Children and Adolescents.Life (Basel, Switzerland) · 2023Article
- Hypertension among adolescents in sub-Saharan Africa: a systematic review.Frontiers in cardiovascular medicine · 2023Review
- Endothelial Dysfunction in South African Youth Living With Perinatally Acquired Human Immunodeficiency Virus on Antiretroviral Therapy.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020Article
- HIV-Associated CKDs in Children and Adolescents.Kidney international reports · 2020Article
- Multisystem impairment in South African adolescents with Perinatally acquired HIV on antiretroviral therapy (ART).Journal of the International AIDS Society · 2019Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundLittle is known about renal pathology among perinatally HIV-infected children and adolescents in Africa. We assessed the prevalence of risk factors for chronic kidney disease in South African children and adolescents with perinatally acquired HIV-1 (HIV+) on antiretroviral therapy (ART) and HIV-negative children and adolescents.
methodsHIV+ youth aged 9-14 years, on ART for > 6 months and age-matched HIV-negative children and adolescents were eligible for assessment of proteinuria and microalbuminuria using urine dipstick and Vantage analyser method. Blood pressure, estimated glomerular filtration rate, HIV-related variables and metabolic co-morbidities were assessed at enrolment.
resultsAmong 620 children and adolescents, 511 were HIV+. The median age was 12.0 years and 50% were female. In HIV+ children and adolescents, 425 (83.2%) had a CD4 count > 500 cells/mm
conclusionsProteinuria and microalbuminuria appear to be uncommon in this population. Follow up of those with microalbuminuria may inform long-term outcomes and management of this growing population of HIV+ youth.
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