Evidence map›Paper›PMID 30219850›Full record

ArticleBioinformatics (Oxford, England)2019

BhGLM: Bayesian hierarchical GLMs and survival models, with applications to genomics and epidemiology.

Nengjun Yi, Zaixiang Tang, Xinyan Zhang, Boyi Guo

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

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  5. Plasma pTau217 predicts continuous brain amyloid levels in preclinical and early Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
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  16. Diet Quality and the Gut Microbiota in Women Living in Alabama.American journal of preventive medicine · 2022
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nengjun YiDepartment of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA.
Zaixiang TangDepartment of Biostatistics, School of Public Health, Medical College of Soochow University, Suzhou, China.
Xinyan ZhangDepartment of Biostatistics, Jiann-Ping Hsu College of Public Health, Georgia Southern University, Statesboro, GA, USA.
Boyi GuoDepartment of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA.

Funding

Bayesian Methods for Mapping Complex Epistatic GenesR01GM069430 · NIGMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI YI, NENGJUN · 2005 to 2013
$2.3M
Deciphering How Esco2 Loss Acts as a Penetrance ModifierR01CA216108 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI PARANT, JOHN M · 2017 to 2021
$1.9M
NCI NIH HHS R01 CA216108NIGMS NIH HHS R01 GM069430
6 · The paper itself

Abstract

summaryBhGLM is a freely available R package that implements Bayesian hierarchical modeling for high-dimensional clinical and genomic data. It consists of functions for setting up various Bayesian hierarchical models, including generalized linear models (GLMs) and Cox survival models, with four types of prior distributions for coefficients, i.e. double-exponential, Student-t, mixture double-exponential and mixture Student-t. These functions adapt fast and stable algorithms to estimate parameters. BhGLM also provides functions for summarizing results numerically and graphically and for evaluating predictive values. The package is particularly useful for analyzing large-scale molecular data, i.e. detecting disease-associated variables and predicting disease outcomes. We here describe the models, algorithms and associated features implemented in BhGLM. AVAILABILITY AND IMPLEMENTATION: The package is freely available from the public GitHub repository, https://github.com/nyiuab/BhGLM.

Indexed as

AlgorithmsGenomicsBayes TheoremLinear ModelsProportional Hazards Models

Identifiers

PMID30219850
PMCPMC7963076

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.