Trial reportBrazilian journal of anesthesiology (Elsevier)
[Combined spinal-epidural block for labor analgesia. Comparative study with continuous epidural block].
Trial report in Brazilian journal of anesthesiology (Elsevier). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 19 citations in OpenAlex.
- The significance of different intervertebral spaces in combined spinal epidural anesthesia in cesarean section.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024Trial
- Effects of 0.15% ropivacaine alone and combination with sufentanil on epidural labor analgesia and adverse reactions.African health sciences · 2023Trial
- Acupoint Injection Decreases Anesthetic Cosumption during Combined Spinal-Epidural and Patient-Controlled Epidural Labor Analgesia.Chinese journal of integrative medicine · 2022Trial
- Intrathecal dexmedetomidine improves epidural labor analgesia effects: a randomized controlled trial.The Journal of international medical research · 2021Trial
- A Systematic Review of Contemporary and Emerging Analgesia Techniques for Natural Labor-Patient-Centered Approaches and Technological Advances.Journal of clinical medicine · 2025Review
- Effects of combined spinal-epidural anesthesia and epidural analgesia on pain and blood pressure in preeclamptic women undergoing painless delivery.American journal of translational research · 2025Article
- Exploration of fever characteristics in parturients under continuous temperature monitoring during labor analgesia and analysis of the impact on maternal and neonatal outcomes: an observational study.Frontiers in global women's health · 2025Article
- Combined spinal-epidural analgesia and epidural analgesia induced maternal fever with a similar timing during labor-A randomized controlled clinical trial.Frontiers in medicine · 2022Article
- Parturition in Mammals: Animal Models, Pain and Distress.Animals : an open access journal from MDPI · 2021Review
- Analgesic Effects of Epidural Labor Analgesia at Different Periods and Its Effects on Maternal and Infant Outcomes and MiRNA-146b Level.Journal of healthcare engineering · 2021Article
- A comparative study of epidural labor analgesia and natural delivery without analgesia.American journal of translational research · 2021Article
- Progress of labor and obstetric outcome in parturients with combined spinal-epidural analgesia for labor: A comparative study.Annals of African medicineArticle
- Obstetric anesthesia: pearls and pitfalls in anesthesia for cesarean delivery.Brazilian journal of anesthesiology (Elsevier)Article
- [Neuraxial labor analgesia: a literature review: a letter to the editor].Brazilian journal of anesthesiology (Elsevier)Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionLumbar epidural block is an effective and routinely used technique for labor pain relief, and the combined spinal-epidural block has the benefit of using lower doses of local anesthetics and rapid onset of analgesia. The objective of this study was to evaluate the effectiveness and safety of two anesthetic techniques: combined spinal-epidural block and continuous epidural block in pregnant women for labor analgesia.
methodsEighty patients, ASA II and III, with cephalic presentation and cervical dilation between 5 and 6 centimeters, undergoing labor analgesia, allocated in two groups according to the anesthetic technique: combined spinal-epidural (GI) and continuous epidural (GII). Pain severity before the blockade, time to complete analgesia, degree of motor blockade, time to full cervical dilation, duration of the second stage of labor, pain severity during the 1
resultsAt the time of anesthesia, pain severity was similar in both groups. Pain relief was faster in GI (4.5±1.5min) when compared to GII (11.6±4.6min) p=0.01; pain scores in the first and second stages of delivery were lower in GI (0.9±0.3 and 1.8±0.7, respectively) when compared to GII (1.9±0.6 and 2.2±0.5, respectively), with p=0.01 only in the first stage of labor; there was need for local anesthetics supplementation in GII; there were more frequent spontaneous deliveries in GI (80% of patients) than in GII (50%) (p=0.045) and more frequent use of instrumental (p=0.03) in GII (12 patients) compared to GI (4 patients); the frequency of cesarean deliveries was significantly higher (p=0.02) in Group II than in Group I, with 4 cases in GI and 8 cases in GII; absence of maternal cardiocirculatory and respiratory changes and neonatal repercussions; more frequent pruritus in GI (10 patients) and (0 patients in GII) (p=0.02).
conclusionThe combined blockade proved to be effective with better quality of analgesia and greater comfort for pregnant women, constituting a good option for the practice of obstetric analgesia.
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