Evidence map›Paper›PMID 30219107›Full record

ArticleSystematic reviews2018

Sustaining knowledge translation interventions for chronic disease management in older adults: protocol for a systematic review and network meta-analysis.

Andrea C Tricco, Julia E Moore, Nicole Beben, Ross C Brownson, David A Chambers, Lisa R Dolovich, Annemarie Edwards, Lee Fairclough, Paul P Glasziou, Ian D Graham and 15 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Systematic reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Andrea C TriccoLi Ka Shing Knowledge Institute, St. Michael's Hospital, Knowledge Translation Program, 209 Victoria Street, East Building, Room 716, Toronto, Ontario, M5B 1W8, Canada.
Julia E MooreLi Ka Shing Knowledge Institute, St. Michael's Hospital, Knowledge Translation Program, 209 Victoria Street, East Building, Room 716, Toronto, Ontario, M5B 1W8, Canada.
Nicole BebenCanadian Partnership Against Cancer, 1 University Avenue, Suite 300, Toronto, Ontario, M5J 2P1, Canada.
Ross C BrownsonPrevention Research Center in St. Louis, Brown School, Washington University in St. Louis, St. Louis, MO, 63130, USA.
David A ChambersNational Cancer Institute, 9609 Medical Center Drive, Room 3E414, Rockville, MD, 20850, USA.
Lisa R DolovichLeslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Room 607, Toronto, Ontario, M5S 3M2, Canada.
Annemarie EdwardsCanadian Partnership Against Cancer, 1 University Avenue, Suite 300, Toronto, Ontario, M5J 2P1, Canada.
Lee FaircloughHealth Quality Ontario, 130 Bloor Street West, 10th floor, Toronto, Ontario, M5S 1N5, Canada.
Paul P GlasziouFaculty of Health Sciences and Medicine, Bond University, Robina, Queensland, 4226, Australia.
Ian D GrahamSchool of Epidemiology and Public Health, University of Ottawa, 600 Peter Morand Crescent, Ottawa, K1G 5Z3, Canada.
Brenda R HemmelgarnDepartments of Medicine and Community Health Sciences, University of Calgary, TRW Building, 3rd Floor, 3280 Hospital Drive NW, Calgary, Alberta, T2N 4Z6, Canada.
Bev HolmesThe Michael Smith Foundation for Health Research (MSFHR), 200 - 1285 West Broadway, Vancouver, British Columbia, V6H 3X8, Canada.
Wanrudee IsaranuwatchaiLi Ka Shing Knowledge Institute, St. Michael's Hospital, Knowledge Translation Program, 209 Victoria Street, East Building, Room 716, Toronto, Ontario, M5B 1W8, Canada.
Chantelle C LachanceLi Ka Shing Knowledge Institute, St. Michael's Hospital, Knowledge Translation Program, 209 Victoria Street, East Building, Room 716, Toronto, Ontario, M5B 1W8, Canada.
France LegareDépartement de Médecine Sociale et Préventive, Faculté de médecine, Université Laval Pavillon Ferdinand-Vandry1050, avenue de la Médecine, local 2431, Québec, Québec, G1V 0A6, Canada.
Jessie McGowanSchool of Epidemiology and Public Health, University of Ottawa, 600 Peter Morand Crescent, Ottawa, K1G 5Z3, Canada.
Sumit R MajumdarDepartment of Medicine, University of Alberta, 13-103 Clinical Sciences Building, 11350-83 Avenue, Edmonton, Alberta, T6G 2G3, Canada.
Justin PresseauSchool of Epidemiology and Public Health, University of Ottawa, 600 Peter Morand Crescent, Ottawa, K1G 5Z3, Canada.
Janet E SquiresSchool of Epidemiology and Public Health, University of Ottawa, 600 Peter Morand Crescent, Ottawa, K1G 5Z3, Canada.
Henry T StelfoxDepartments of Critical Care Medicine, Medicine and Community Health Sciences, University of Calgary, 2500 University Drive NW, Calgary, Alberta, T2N 1N4, Canada.
Lisa StriflerLi Ka Shing Knowledge Institute, St. Michael's Hospital, Knowledge Translation Program, 209 Victoria Street, East Building, Room 716, Toronto, Ontario, M5B 1W8, Canada.
Kristine ThompsonLi Ka Shing Knowledge Institute, St. Michael's Hospital, Knowledge Translation Program, 209 Victoria Street, East Building, Room 716, Toronto, Ontario, M5B 1W8, Canada.
Trudy Van der WeijdenDepartment of Family Medicine, Maastricht University, CAPHRI Care and Public Health Research Institute, Universiteitssingel 40, 6229 ER, Maastricht, The Netherlands.
Areti Angeliki VeronikiLi Ka Shing Knowledge Institute, St. Michael's Hospital, Knowledge Translation Program, 209 Victoria Street, East Building, Room 716, Toronto, Ontario, M5B 1W8, Canada.
Sharon E StrausLi Ka Shing Knowledge Institute, St. Michael's Hospital, Knowledge Translation Program, 209 Victoria Street, East Building, Room 716, Toronto, Ontario, M5B 1W8, Canada. sharon.straus@utoronto.ca.

Funding

CIHR 154334
6 · The paper itself

Abstract

backgroundFailure to sustain knowledge translation (KT) interventions impacts patients and health systems, diminishing confidence in future implementation. Sustaining KT interventions used to implement chronic disease management (CDM) interventions is of critical importance given the proportion of older adults with chronic diseases and their need for ongoing care. Our objectives are to (1) complete a systematic review and network meta-analysis of the effectiveness and cost-effectiveness of sustainability of KT interventions that target CDM for end-users including older patients, clinicians, public health officials, health services managers and policy-makers on health care outcomes beyond 1 year after implementation or the termination of initial project funding and (2) use the results of this review to complete an economic analysis of the interventions identified to be effective.

methodsFor objective 1, comprehensive searches of relevant electronic databases (e.g. MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials), websites of health care provider organisations and funding agencies will be conducted. We will include randomised controlled trials (RCTs) examining the impact of a KT intervention targeting CDM in adults aged 65 years and older. To examine cost, economic studies (e.g. cost, cost-effectiveness analyses) will be included. Our primary outcome will be the sustainability of the delivery of the KT intervention beyond 1 year after implementation or termination of study funding. Secondary outcomes will include behaviour changes at the level of the patient (e.g. symptom management) and clinician (e.g. physician test ordering) and health system (e.g. cost, hospital admissions). Article screening, data abstraction and risk of bias assessment will be completed independently by two reviewers. Using established methods, if the assumption of transitivity is valid and the evidence forms a connected network, Bayesian random-effects pairwise and network meta-analysis will be conducted. For objective 2, we will build a decision analytic model comparing effective interventions to estimate an incremental cost-effectiveness ratio. DISCUSSION: Our results will inform knowledge users (e.g. patients, clinicians, policy-makers) regarding the sustainability of KT interventions for CDM. Dissemination plan of our results will be tailored to end-users and include passive (e.g. publications, website posting) and interactive (e.g. knowledge exchange events with stakeholders) strategies. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42018084810.

Indexed as

Chronic DiseaseDisease ManagementTranslational Research, BiomedicalAgedCost-Benefit AnalysisHumansNetwork Meta-Analysis as TopicSystematic Reviews as TopicChronic disease managementIntegrated knowledge translationKnowledge translationOlder adultsSustainability

Identifiers

PMID30219107
PMCPMC6138921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.