ArticleNeuroImage. Clinical2018
Imaging fast electrical activity in the brain during ictal epileptiform discharges with electrical impedance tomography.
Article in NeuroImage. Clinical, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 35 citations in OpenAlex.
- Dynamic Cerebral Perfusion Electrical Impedance Tomography: A Neuroimaging Technique for Bedside Cerebral Perfusion Monitoring During Mannitol Dehydration.Bioengineering (Basel, Switzerland) · 2025Article
- State-of-the-art preclinical techniques to study the impact of spreading depolarizations in awake rodents.The journal of headache and pain · 2025Review
- Can a Cochlear Implant Be Used as an Electrical Impedance Tomography Device?International journal for numerical methods in biomedical engineering · 2025Article
- Temperature and Frequency Dependence of Human Cerebrospinal Fluid Dielectric Parameters.Sensors (Basel, Switzerland) · 2024Article
- Electrical Impedance Tomography: From the Traditional Design to the Novel Frontier of Wearables.Sensors (Basel, Switzerland) · 2023Review
- Advances in electrical impedance tomography-based brain imaging.Military Medical Research · 2022Review
- Advances of deep learning in electrical impedance tomography image reconstruction.Frontiers in bioengineering and biotechnology · 2022Review
- Imaging of focal seizures with Electrical Impedance Tomography and depth electrodes in real time.NeuroImage · 2021Article
- Electrical Impedance Tomography - Recent Applications and Developments.Journal of electrical bioimpedance · 2021Article
- Comparison of electrical impedance tomography and intracranial pressure during dehydration treatment of cerebral edema.NeuroImage. Clinical · 2019Article
- Recognition of Lung Volume Condition based on Phase Space Mapping Using Electrical Impedance Tomography.Journal of electrical bioimpedance · 2019Article
- Applications of Electrical Impedance Tomography in Neurology.Basic and clinical neuroscienceReview
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Electrical Impedance Tomography (EIT) is an emerging medical imaging technique which can produce tomographic images of internal impedance changes within an object using non-penetrating surface electrodes. It has previously been used to image impedance changes due to neuronal depolarisation during evoked potentials in the rat somatosensory cortex with a resolution of 2 ms and <200 μm, using an epicortical electrode array. The purpose of this work was to use this technique to elucidate the intracortical spatiotemporal trajectory of ictal spike-and-wave discharges (SWDs), induced by electrical stimulation in an acute rat model of epilepsy, throughout the cerebral cortex. Seizures lasting 16.5 ± 5.3 s with repetitive 2-5 Hz SWDs were induced in five rats anaesthetised with fentanyl-isoflurane. Transfer impedance measurements were obtained during each seizure with a 57-electrode epicortical array by applying 50 μA current at 1.7 kHz to two electrodes and recording voltages from all remaining electrodes. Images were reconstructed from averaged SWD-related impedance traces obtained from EIT measurements in successive seizures. We report the occurrence of reproducible impedance changes during the initial spike phase, which had an early onset in the whisker barrel cortex and spread posteriorly, laterally and ventrally over 20 ms (p < 0.03125, N = 5). These findings, which confirm and extend knowledge of SWD initiation and expression, suggest that EIT is a valuable neuroimaging tool for improving understanding of neural circuits implicated in epileptic phenomena.
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