Evidence map›Paper›PMID 30218684›Full record

ArticleJournal of virological methods2018

A convenient colorimetric assay for the quantification of porcine epidemic diarrhea virus and neutralizing antibodies.

Pankaj Singh, Gagandeep Singh, Jenna Karsky, Eric Nelson, Sheela Ramamoorthy

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virological methods, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Pankaj SinghDepartment of Microbiological Sciences, North Dakota State University, Fargo, ND, United States.
Gagandeep SinghDepartment of Microbiological Sciences, North Dakota State University, Fargo, ND, United States.
Jenna KarskyDepartment of Microbiological Sciences, North Dakota State University, Fargo, ND, United States.
Eric NelsonAnimal Disease Research and Diagnostic Laboratory, S. Dakota State University, Brookings, SD, United States.
Sheela RamamoorthyDepartment of Microbiological Sciences, North Dakota State University, Fargo, ND, United States. Electronic address: Ramamoorthysheela.ramamoorthy@ndus.edu.
North Dakota State University · USSouth Dakota State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neonatal enteritis caused by the porcine epidemic diarrhea virus (PEDV) is an important cause of high mortality and economic losses to the swine industry. Virus neutralization (V/N) assays are commonly requested in diagnostic laboratories for the assessment of protective antibodies. However, the visual assessment of viral cytopathic effects by operators to determine antibody titers or for viral quantification is a tedious, subjective and time-consuming process, especially when high volume testing is involved. To improve the ease of testing, a colorimetric virus neutralization and TCID

Indexed as

AnimalsAntibodies, NeutralizingAntibodies, ViralColorimetryCoronavirus InfectionsCytopathogenic Effect, ViralEnzyme-Linked Immunosorbent AssayNeutralization TestsPorcine epidemic diarrhea virusReproducibility of ResultsROC CurveSwineSwine DiseasesAntibodies, NeutralizingAntibodies, ViralColorimetricPEDVPlaque assayPorcine epidemic diarrhea virusTCID(50)Virus neutralization

Identifiers

PMID30218684
PMCPMC7113882
OpenAlexW2890098488

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.