ArticleGastroenterology2018
Detection and Analysis of Circulating Epithelial Cells in Liquid Biopsies From Patients With Liver Disease.
Abstract read
In one paragraph
Article in Gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Utility of Liquid Biopsy Analysis in Detection of Hepatocellular Carcinoma, Determination of Prognosis, and Disease Monitoring: A Systematic Review.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2020Pooled it
- The alternative splicing landscape of hepatocellular carcinoma and its potential for HCC detection.Hepatology communications · 2026Article
- Molecular Deconvolution of Circulating "Other Cells": A Reliable Predictive Marker of Therapy Response and Survival in Neuroendocrine Tumor Patients ReceivingCancer medicine · 2026Article
- Circulating tumor cells: Blood-based detection, molecular biology, and clinical applications.Cancer cell · 2025Review
- Liquid biopsy in hepatocellular carcinoma: Challenges, advances, and clinical implications.Clinical and molecular hepatology · 2025Review
- Prognostic prediction signature and molecular subtype for liver cancer: A CTC/CTM‑related gene prediction model and independent external validation.Oncology letters · 2024Article
- Article
- Liquid Biopsy in Hepatocellular Carcinoma: The Significance of Circulating Tumor Cells in Diagnosis, Prognosis, and Treatment Monitoring.International journal of molecular sciences · 2023Review
- Review
- Characterizing the epithelial-mesenchymal transition status of circulating tumor cells in head and neck squamous cell carcinoma.Head & neck · 2022Article
- [Application of liquid biopsy in early screening and recurrence prediction of hepatocellular carcinoma].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022Article
- When Tissue is an Issue the Liquid Biopsy is Nonissue: A Review.Oncology and therapy · 2021Review
- Review
- Animal Models for Hepatitis B: Does the Supply Meet the Demand?Gastroenterology · 2021Article
- Cell release during perfusion reflects cold ischemic injury in rat livers.Scientific reports · 2020Article
- Somatic copy number profiling from hepatocellular carcinoma circulating tumor cells.NPJ precision oncology · 2020Article
- ctcRbase: the gene expression database of circulating tumor cells and microemboli.Database : the journal of biological databases and curation · 2020Article
- Emerging trends in modeling human liver diseaseAPL bioengineering · 2019Article
- Detection of Circulating Tumor Cells by Cell Block Technique in Malignant Tumors.Journal of cytologyArticle
- Circulating tumor cells in whole process management of gastrointestinal stromal tumor in a real-life setting.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology AssociationArticle
Corrections and comments
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Authors and funding
15 authors.
Irun BhanCancer Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts; Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Kelly MosessoDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Lipika GoyalCancer Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Julia PhilippCancer Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Mark KalinichCancer Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Joseph W FransesCancer Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Melissa ChozCancer Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts; Center for Engineering in Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Rahmi OkluCenter for Engineering in Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts; Division of Interventional Radiology, Mayo Clinic, Phoenix, Arizona.
Mehmet TonerCenter for Engineering in Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts; Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Shyamala MaheswaranCancer Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts; Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Daniel A HaberCancer Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts; Howard Hughes Medical Institute, Chevy Chase, Maryland.
Andrew X ZhuCancer Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Raymond T ChungDivision of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Martin AryeeCancer Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts; Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
David T TingCancer Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts. Electronic address: dting1@mgh.harvard.edu.
Funding
Medical Scientist Training ProgramT32GM007753 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WALENSKY, LOREN DAVID · 1985 to 2021
$50.0MPilot & Feasibility ProgramP30DK043351 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Ramnik J Xavier · 1991 to 2026
$35.3MPoint-of care Microfluidics for Early Detection of CancerU01EB012493 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI HABER, DANIEL A., TONER, MEHMET · 2010 to 2018
$19.6MRESEARCH TRAINING IN DIGESTIVE DISEASES AND NUTRITIONT32DK007191 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI RAYMOND T CHUNG · 1986 to 2026
$14.6MTraining Grant in Quantitative Sciences for Cancer ResearchT32CA009337 · NCI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI QUACKENBUSH, JOHN, TRIPPA, LORENZO · 1986 to 2025
$12.3MModeling Metastasis and Acquired Drug Resistance Using Circulating Tumor CellsR01CA129933 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI Daniel A. Haber · 2008 to 2026
$7.5MPatient-Oriented Research on Hepatitis in Special PopulationsK24DK078772 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI CHUNG, RAYMOND T · 2007 to 2016
$1.6MCirculating tumor cells in hepatocellular carcinomaR03CA172738 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI TONER, MEHMET · 2013 to 2014
$171kMechanically mediated genomic changes during the metastatic cascadeF30CA224588 · NCI · HARVARD MEDICAL SCHOOL · PI KALINICH, MARK · 2018 to 2019
$86kHoward Hughes Medical InstituteNCI NIH HHS F30 CA224588NCI NIH HHS R01 CA129933NCI NIH HHS R03 CA172738NIBIB NIH HHS U01 EB012493NIDDK NIH HHS K24 DK078772NIDDK NIH HHS P30 DK043351NIDDK NIH HHS T32 DK007191NIGMS NIH HHS T32 GM007753
Abstract
PubMed holds no abstract for this paper.
Indexed as
Epithelial CellsAdultAgedAged, 80 and overCarcinoma, HepatocellularChronic DiseaseFemaleHumansLiquid BiopsyLiver DiseasesLiver NeoplasmsMaleMiddle AgedNeoplastic Cells, CirculatingBiomarkerDetectionHepatitisLiver Cancer Screening
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.