Evidence map›Paper›PMID 30218617›Full record

Observational studyBasic & clinical pharmacology & toxicology2019

Cystatin C measurement leads to lower metformin dosage in elderly type 2 diabetic patients.

Tomáš Šálek, Alena Adamíková

Abstract readObservational Study
In one paragraph

Observational study in Basic & clinical pharmacology & toxicology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Tomáš ŠálekDepartment of Clinical Biochemistry and Pharmacology, Tomas Bata Hospital in Zlín a. s., Zlín, Czech Republic.
Alena AdamíkováDiabetes Center, Tomas Bata Hospital in Zlín, a. s., Zlín, Czech Republic.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to provide evidence for the hypothesis that estimated glomerular filtration rate from serum Cystatin C (eGFRcys) is better to be determined for all elderly type 2 diabetes mellitus (T2DM) patients based on eGFRcys upward and downward reclassification rate for hypothetical metformin dose reduction by eGFRcys at the GFR decision point of 45 mL/min/1.73 m

Indexed as

AgedAged, 80 and overAge FactorsCreatinineCystatin CDiabetes Mellitus, Type 2Dose-Response Relationship, DrugGlomerular Filtration RateHumansHypoglycemic AgentsMetforminRenal Insufficiency, ChronicRetrospective StudiesCreatinineCystatin CHypoglycemic AgentsMetformincreatininecystatin Cestimated glomerular filtration rateglomerular filtrationmetformin

Identifiers

PMID30218617
PMCPMC7379635

What OpenQuestion holds

Texttitle and abstract
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.