ReviewMovement disorders : official journal of the Movement Disorder Society2018
The clinical features, underlying immunology, and treatment of autoantibody-mediated movement disorders.
Review in Movement disorders : official journal of the Movement Disorder Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- Autoimmune Movement Disorders Complicating Treatment with Immune Checkpoint Inhibitors.Movement disorders clinical practice · 2024Pooled it
- Movement disorders in primary central nervous system lymphoma: two unreported cases and a review of literature.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Pooled it
- WONOEP XVII appraisal: The immunopathogenesis of epilepsy.Epilepsia · 2026Review
- Protracted Presentation of Anti-LGI 1 Encephalitis Associated with Prostate Cancer: A Case Report.Movement disorders clinical practice · 2025Article
- Deep brain stimulation (DBS) in movement disorders management: exploring therapeutic efficacy, neurobiological mechanisms, and clinical implications.Annals of medicine and surgery (2012) · 2025Review
- Paraneoplastic Cerebellar Degeneration Associated with Breast Cancer: A Case Report and a Narrative Review.Brain sciences · 2024Review
- Back to the future: encephalitis lethargica as an autoimmune disorder?Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Review
- Movement disorders in autoimmune encephalitis: an update.Journal of neurology · 2023Review
- Clinical Features and Neuroimaging Findings of Neuropil Antibody-Positive Idiopathic Sporadic Ataxia of Unknown Etiology.Cerebellum (London, England) · 2023Article
- Autoimmune encephalitis: recent clinical and biological advances.Journal of neurology · 2023Article
- Article
- Association between clinical factors and orofacial dyskinesias in anti-N-methyl-D-aspartate receptor encephalitis.Brain and behavior · 2022Article
- Diagnosis and Clinical Features in Autoimmune-Mediated Movement Disorders.Journal of movement disorders · 2022Article
- Clinical features and outcome of patients with autoimmune cerebellar ataxia evaluated with the Scale for the Assessment and Rating of Ataxia.European journal of neurology · 2022Article
- Stiff-person syndrome with paraneoplastic neurological syndrome: a case report and literature review.American journal of translational research · 2022Article
- Development of Diagnosis Model for Early Lung Nodules Based on a Seven Autoantibodies Panel and Imaging Features.Frontiers in oncology · 2022Article
- The autoantibody-mediated encephalitides: from clinical observations to molecular pathogenesis.Journal of neurology · 2021Review
- Involuntary movement in stiff-person syndrome with amphiphysin antibodies: A case report.Medicine · 2021Article
- Clinical diagnosis of LGI1 antibody encephalitis in an 83-year-old woman.BMJ case reports · 2021Article
- Treatment of Movement Disorder Emergencies in Autoimmune Encephalitis in the Neurosciences ICU.Neurocritical care · 2020Review
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
Abstract
An increasing number of movement disorders are associated with autoantibodies. Many of these autoantibodies target the extracellular domain of neuronal surface proteins and associate with highly specific phenotypes, suggesting they have pathogenic potential. Below, we describe the phenotypes associated with some of these commoner autoantibody-mediated movement disorders, and outline increasingly well-established mechanisms of autoantibody pathogenicity which include antigen downregulation and complement fixation. Despite these advances, and the increasingly robust evidence for improved clinical outcomes with early escalation of immunotherapies, the underlying cellular immunology of these conditions has received little attention. Therefore, here, we outline the likely roles of T cells and B cells in the generation of autoantibodies, and reflect on how these may guide both current immunotherapy regimes and our future understanding of precision medicine in the field. In addition, we summarise potential mechanisms by which these peripherally-driven immune responses may reach the central nervous system. We integrate this with the immunologically-relevant clinical observations of preceding infections, tumours and human leucocyte antigen-associations to provide an overview of the therapeutically-relevant underlying adaptive immunology in the autoantibody-mediated movement disorders. © 2018 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.