ArticleJournal of medical systems2018
Validation of a Sequential Organ Failure Assessment Score using Electronic Health Record Data.
Article in Journal of medical systems, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Oxygen-Saturation Targets for Critically Ill Adults Receiving Mechanical Ventilation.The New England journal of medicine · 2022Trial
- Transcranial Doppler findings in patients with COVID-19: a prospective observational study.Arquivos de neuro-psiquiatria · 2026Observational
- Automated Calculation of Sequential Organ Failure Assessment (SOFA) Score in the Intensive Care Unit: Algorithm Development, Validation, and Association With 30-Day Mortality.Acta anaesthesiologica Scandinavica · 2026Article
- Clinical Characteristics and Outcomes in Patients Aged ≥80 Years Treated in the Intensive Care Units of a Large Multispecialty Metropolitan Hospital in Poland.Journal of clinical medicine · 2025Article
- Automated APACHE II and SOFA score calculation using real-world electronic medical record data in a single center.Journal of clinical monitoring and computing · 2023Article
- Toxic Metabolic Encephalopathy in Hospitalized Patients with COVID-19.Neurocritical care · 2021Observational
- COVID-19 and Co-infection in Children: The Indian Perspectives.Journal of tropical pediatrics · 2021Observational
- Rate of intra-arrest epinephrine administration and early post-arrest organ failure after in-hospital cardiac arrest.Resuscitation · 2020Article
- Validation of an Electronic Pediatric Index of Mortality 2 Score in a Mixed Quaternary PICU.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2020Observational
- The Blessing and the Curse of the Administrative Database.Annals of the American Thoracic Society · 2020Article
- SOFA and qSOFA at admission to the emergency department: Diagnostic sensitivity and relation with prognosis in patients with suspected infection.Turkish journal of emergency medicine · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
The sequential organ failure assessment (SOFA) score is a scoring system commonly used in critical care to assess severity of illness. Automated calculation of the SOFA score using existing electronic health record data would broaden its applicability. We performed a manual validation of an automated SOFA score previously developed at our institution. A retrospective analysis of a random subset of 300 patients from a previously published randomized trial of critically ill adults was performed, with manual validation of SOFA scores from the date of initial intensive care unit admission. Spearman's rank correlation coefficient, weighted Cohen's kappa, and Bland-Altman plots were used to assess agreement between manual and electronic versions of SOFA scores and between manual and electronic versions of their individual components. There was high agreement between manual and electronic SOFA scores (Spearman's rank correlation coefficient = 0.90, 95% CI 0.87-0.93). Renal and respiratory components had lower agreement (weighted Cohen's kappa = 0.63, 95% CI 0.53-0.73 for renal; weighted Cohen's kappa = 0.77, 95% CI 0.70-0.84 for respiratory). The area under the receiver operating characteristic curve (AUC) for 30-day in-hospital mortality was 0.77 (95% CI 0.68-0.84) for manual SOFA scores and 0.75 (95% CI 0.66-0.83) for automated SOFA scores. Automatic calculation of SOFA scores from the electronic health record is feasible and correlates highly with manually calculated SOFA scores. Both have similar predictive value for 30-day in-hospital mortality.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.