Evidence map›Paper›PMID 30218380›Full record

ArticleArchives of osteoporosis2018

In-hospital care, complications, and 4-month mortality following a hip or proximal femur fracture: the Spanish registry of osteoporotic femur fractures prospective cohort study.

Daniel Prieto-Alhambra, Carlen Reyes, Miguel Sanz Sainz, Jesús González-Macías, Luis Gracia Delgado, Cristina Alonso Bouzón, Sarah Mills Gañan, Damián Mifsut Miedes, Eduardo Vaquero-Cervino, Manuel Francisco Bravo Bardaji and 26 more

Open access · hybridAbstract read
In one paragraph

Article in Archives of osteoporosis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Review
  8. Contemporary pharmacological management of patients after hip fracture: a population-based cohort of over 120,000 patients in Spain.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
  9. Article
  10. Effectiveness of a co-management program with internal medicine on hip fracture patients at a regional hospital in northwest Spain. Co-inter-Monf study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Observational
  11. La Tunisie medicale · 2024
    Article
  12. Article
  13. Article
  14. The grade of instability in fragility fractures of the pelvis correlates with impaired early mobilization.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022
    Observational
  15. Article
  16. The Economic Burden of Severe Osteoporotic Fractures in the French Healthcare Database: The FRACTOS Study.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Article
  17. Observational
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors at 20 institutions in 2 countries.

Daniel Prieto-AlhambraGREMPAL (Grup de Recerca en Epidemiologia de les Malalties Prevalents de l'Aparell Locomotor) Research Group, CIBERFES, IDIAP Jordi Gol (Universitat Autònoma de Barcelona) and Instituto de Salud Carlos III, Av Gran Via de les Corts Catalanes, 587, Atic, 08007, Barcelona, Spain. Daniel.prietoalhambra@ndorms.ox.ac.uk.
Carlen ReyesGREMPAL (Grup de Recerca en Epidemiologia de les Malalties Prevalents de l'Aparell Locomotor) Research Group, CIBERFES, IDIAP Jordi Gol (Universitat Autònoma de Barcelona) and Instituto de Salud Carlos III, Av Gran Via de les Corts Catalanes, 587, Atic, 08007, Barcelona, Spain.
Miguel Sanz SainzIIS Aragón (Instituto de Investigación Sanitaria de Aragón), Hospital Universitario Miguel Servet, Padre Arrupe, s/n, 50009, Zaragoza, Spain.
Jesús González-MacíasIDIVAL (Instituto de Investigación Marqués de Valdecilla), HUMV (Hospital Universitario Marqués de Valdecilla), UC (Universidad de Cantabria), Av de Valdecilla sn, 39011, Santander, Cantabria, Spain.
Luis Gracia DelgadoHospital Universitario Reina Sofía de Cordoba, Av Menendez Pidal, 14004, Córdoba, Spain.
Cristina Alonso BouzónGeriatric Unit, Hospital Universitario de Getafe, Carr. De Madrid - Toledo, Km 12,500, 28905, Getafe, Madrid, Spain.
Sarah Mills GañanTraumatology and Orthopaedics Unit, Hospital Universitario La Paz, Paseo de la Castellana, 261, 28046, Madrid, Spain.
Damián Mifsut MiedesHospital Clínico de Valencia, Av de Blasco Ibáñez, 17, 46010, Valencia, Spain.
Eduardo Vaquero-CervinoComplejo Hospitalario de Pontevedra, Av Montecelo, 0, 36164, Casas Novas, Pontevedra, Spain.
Manuel Francisco Bravo BardajiHospital Regional Universitario de Malaga, Av. de Carlos Haya, s/n, 29010, Málaga, Spain.
Laura Ezquerra HerrandoF.E.A of the Traumatology and Orthopaedics Unit, Hospital Clínico Universitario Lozano Blesa, Av. San Juan Bosco, 15, 50009, Zaragoza, Spain.
Fátima Brañas BaztánGeriatric Unit, Hospital Universitario Infanta Leonor, Gran Vía del Este, 80, 28031, Madrid, Spain.
Bartolomé Lladó FerrerHospital Son Llàtzer, Carretera de Manacor, PQ 4 (Son Ferriol), 07198, Palma de Mallorca, Spain.
Ivan Perez-CotoHospital Universitario San Agustín, Camino de Heros, 6, 33401, Avilés, Asturias, Spain.
Gaspar Adrados BuenoInternal Medicine Unit, Hospital Infanta Cristina, Av. de Elvas, s/n, 06080, Badajoz, Spain.
Jesús Mora-FernandezGeriatric Unit, Hospital Clínico San Carlos, calle Prof. Martín Lagos s/n, 28040, Madrid, Spain.
Teresa Espallargas DoñateHospital Obispo Polanco, Av. Ruiz Jarabo, s/n, 44002, Teruel, Spain.
Jorge Martínez-Iñiguez BlascoHospital San Pedro, Calle Piqueras, 98, 26006, Logroño, La Rioja, Spain.
Ignacio Aguado-MaestroHospital Universitario Rio Hortega, Calle Dulzaina, 2, 47012, Valladolid, Spain.
Pilar Sáez-LópezHospital Universitario Fundación Jiménez Díaz, IdiPAZ (Instituto de Investigación del Hospital La Paz), Madrid, Spain.
Monica Salomó DoménechCorporación sanitaria Universitaria Parc Tauli, Parc Taulí, 1, 08208, Sabadell, Barcelona, Spain.
Vicente Climent-PerisTraumatology and Orthopaedics Unit, Hospital Públic Lluis Alcanyis de Xàtiva, Carretera Xátiva-Silla, Km 2, 46800, Xàtiva, Valencia, Spain.
Ángel Díez RodríguezTraumatology and Orthopaedics Unit, Hospital Virgen del Puerto, Paraje Valcorchero, 10600, Plasencia, Cáceres, Spain.
Humberto Kessel SardiñasGeriatric Care Unit, Complejo Hospitalario Torrecárdenas, Calle Hermandad de Donantes de Sangre, 04009, Almería, Spain.
Óscar Tendero GómezHospital Universitari Son Espases, Carr. de Valldemossa, 79, 07120, Palma, Islas Baleares, Spain.
Jordi Teixidor SerraHospital Universitari Vall de Hebron, Passeig de la Vall d'Hebron, 119-129, 08035, Barcelona, Spain.
José Ramón Caeiro-ReyTraumatology and Orthopaedics Unit, Complejo Hospitalario Universitario de Santiago de Compostela, Rúa da Choupana, s/n, 15706, Santiago de Compostela, A Coruña, Spain.
Ignacio Andrés CanoHospital Puerta del Mar, Av. Ana de Viya, 21, 11009, Cádiz, Spain.
Mariano Barrés CarsiHospital Universitari i Politècnic La Fe, Av de Fernando Abril Martorell, 106, 46026, València, Spain.
Iñigo Etxebarria-ForondaDepartment of Orthopaedic, Alto Deba Hospital, Arrasate-Mondragon, Gipuzkoa, Spain.
Juan Dionisio Avilés HernándezOrthogeriatric Unit, Hospital Clínico Universitario Virgen de Arrixaca, Ctra. Madrid-Cartagena, s/n, 30120, El Palmar, Murcia, Spain.
Juan Rodriguez SolisGeriatric Unit, Hospital Universitario de Guadalajara, Calle Donante de Sangre, s/n, 19002, Guadalajara, Spain.
Oscar Torregrosa SuauBone Metabolism Unit, Internal Medicine Unit, Hospital General Universitari d'Elx, Carrer Almazara, 11, 03203, Elche, Alicante, Spain.
Xavier NoguésInternal Medicine Department IMIM (Hospital del Mar Medical Research), CIBER FES ISCIII, Universitat Autónoma de Barcelona, Barcelona, Spain.
Antonio HerreraDepartment of Surgery, Aragón Health Research Institute, University of Zaragoza, Zaragoza, Spain.
Adolfo Díez-PerezMusculoskeletal Research Unit, IMIM-Parc Salut Mar, CIBERFES, Universitat Autònoma de Barcelona, Doctor Aiguader 88, 08003, Barcelona, Spain.
Universitat Autònoma de Barcelona · ESComplejo Hospitalario de Pontevedra · ESComplejo Hospitalario Torrecárdenas · ESComplejo Hospitalario Universitario de Santiago · ESCorporació Sanitària Parc Taulí · ESHospital Alto Deba · ESHospital Clínico San Carlos · ESHospital Clínico Universitario de Valencia · ESHospital Clínico Universitario Lozano Blesa · ESHospital General Universitario de Elche · ESHospital Obispo Polanco · ESHospital Regional Universitario de Málaga · ESHospital San Pedro · ESHospital Son Llatzer · ESHospital Universitari i Politècnic La Fe · ESHospital Universitario de Getafe · ESHospital Universitario de Guadalajara · ESHospital Universitario Fundación Jiménez Díaz · ESHospital Universitario Infanta Cristina · ESHospital Universitario Infanta Leonor · ES

Funding

Department of Health CS-2013-13-012
6 · The paper itself

Abstract

We have characterised 997 hip fracture patients from a representative 45 Spanish hospitals, and followed them up prospectively for up to 4 months. Despite suboptimal surgical delays (average 59.1 hours), in-hospital mortality was lower than in Northern European cohorts. The secondary fracture prevention gap is unacceptably high at 85%. PURPOSE: To characterise inpatient care, complications, and 4-month mortality following a hip or proximal femur fracture in Spain.

methodsDesign: prospective cohort study. Consecutive sample of patients ≥ 50 years old admitted in a representative 45 hospitals for a hip or proximal femur fragility fracture, from June 2014 to June 2016 and followed up for 4 months post-fracture. Patient characteristics, site of fracture, in-patient care (including secondary fracture prevention) and complications, and 4-month mortality are described.

resultsA total of 997 subjects (765 women) of mean (standard deviation) age 83.6 (8.4) years were included. Previous history of fracture/s (36.9%) and falls (43%) were common, and 10-year FRAX-estimated major and hip fracture risks were 15.2% (9.0%) and 8.5% (7.6%) respectively. Inter-trochanteric (44.6%) and displaced intra-capsular (28.0%) were the most common fracture sites, and fixation with short intramedullary nail (38.6%) with spinal anaesthesia (75.5%) the most common procedures. Surgery and rehabilitation were initiated within a mean 59.1 (56.7) and 61.9 (55.1) hours respectively, and average length of stay was 11.5 (9.3) days. Antithrombotic and antibiotic prophylaxis were given to 99.8% and 98.2% respectively, whilst only 12.4% received secondary fracture prevention at discharge. Common complications included delirium (36.1 %) and kidney failure (14.1%), with in-hospital and 4-month mortality of 2.1% and 11% respectively.

conclusionsDespite suboptimal surgical delay, post-hip fracture mortality is low in Spanish hospitals. The secondary fracture prevention gap is unacceptably high at > 85%, in spite of virtually universal anti-thrombotic and antibiotic prophylaxis.

Indexed as

Hospital MortalityAgedAged, 80 and overFemaleFemoral FracturesHip FracturesHumansMaleMiddle AgedOsteoporotic FracturesProspective StudiesRegistriesSpainHip fractureOsteoporosis and patient care managementRegistries

Identifiers

PMID30218380
PMCPMC6153683
OpenAlexW2890919957

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.