Evidence map›Paper›PMID 30218319›Full record

ArticleAIDS and behavior2019

Couple Interdependence Impacts Alcohol Use and Adherence to Antiretroviral Therapy in Malawi.

Amy A Conroy, Stacey A McKenna, Allison Ruark

3 registry-linked trialsAbstract read
In one paragraph

Article in AIDS and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04906616 nacompletednot on this mapstarted 2021, after this paper: background citation

An Economic and Relationship-strengthening Intervention for HIV-affected Couples Who Drink Alcohol in Malawi

TypeinterventionalSponsorUniversity of California, San FranciscoRan2021 to 2023Enrolled156ConditionsHIV/AIDS, Alcohol AbuseArmsMlambe
NCT05756790 nacompletednot on this mapstarted 2023, after this paper: background citation

Couple-Based Motivational Interviewing With Mobile Breathalyzers to Reduce Alcohol Use in South Africa

TypeinterventionalSponsorUniversity of California, San FranciscoRan2023 to 2024Enrolled186ConditionsHIV/AIDS, Alcohol AbuseArmsMotivational Interviewing, Motivational Interviewing plus Breathalyzer
NCT06367348 narecruitingnot on this mapstarted 2025, after this paper: background citation

Mlambe: A Randomized Controlled Trial of an Economic and Relationship-Strengthening Intervention to Reduce Alcohol Use in Malawi

TypeinterventionalSponsorUniversity of California, San FranciscoRan2025 to 2028Enrolled500ConditionsHIV/AIDS, Alcohol AbuseArmsMlambe
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. A Mixed-Methods Systematic Review: Infidelity, Romantic Jealousy and Intimate Partner Violence against Women.International journal of environmental research and public health · 2020
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  17. Managing multimorbidity together: relationship dynamics and dual medication adherence for hypertension and HIV in Malawi.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2025
    Observational
  18. Article
  19. Relationship Dynamics and Young Women's Contraceptive Use.Sexuality research & social policy : journal of NSRC : SR & SP · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Amy A ConroyDivision of Prevention Sciences, Department of Medicine, Center for AIDS Prevention Studies, University of California San Francisco, 550 16th Street, 3rd Floor, San Francisco, CA, USA. amy.conroy@ucsf.edu.ORCID http://orcid.org/0000-0002-0609-5077
Stacey A McKennaStacey McKenna, LLC, Fort Collins, CO, USA.
Allison RuarkDepartment of Medicine, Brown University, Providence, RI, USA.

Funding

HIV and Other Infectious Consequences of Substance UseT32DA013911 · NIDA · MIRIAM HOSPITAL · PI TRACI C GREEN, JOSIAH D RICH · 2001 to 2026
$9.6M
Relationship Factors and Engagement in HIV Care in Malawi: A Dyadic InvestigationK01MH107331 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CONROY, AMY ANNE · 2016 to 2019
$773k
National Institute of Drug Abuse T32DA13911National Institute of Mental Health (US) K01MH107331NIDA NIH HHS T32 DA013911NIMH NIH HHS K01 MH107331
6 · The paper itself

Abstract

In sub-Saharan Africa, harmful alcohol use among male drinkers is high and has deleterious consequences on adherence to antiretroviral therapy (ART), HIV clinical outcomes, and couple relationship dynamics. We conducted in-depth qualitative interviews with 25 Malawian couples on ART to understand how relationships influence adherence to ART, in which alcohol use emerged as a major theme. Almost half of men (40%) reported current or past alcohol use. Although alcohol use was linked to men's non-adherence, women buffered this harm by encouraging husbands to reduce alcohol use and by offering adherence support when men were drinking. Men's drinking interfered with being an effective treatment guardian for wives on ART and also weakened couple support systems needed for adherence. Relationship challenges including food insecurity, intimate partner violence, and extramarital relationships appeared to exacerbate the negative consequences of alcohol use on ART adherence. In this setting, alcohol may be best understood as a couple-level issue. Alcohol interventions for people living with HIV should consider approaches that jointly engage both partners.

Indexed as

Alcohol DrinkingAdultAnti-HIV AgentsDrug MonitoringFemaleHealth SurveysHIV InfectionsHumansInterpersonal RelationsMalawiMaleMedication AdherenceMiddle AgedSexual PartnersSpousesAnti-HIV AgentsAdherenceAlcoholAntiretroviral therapyCouplesHIV/AIDSSub-Saharan Africa

Identifiers

PMID30218319
PMCPMC7232967

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.