Evidence map›Paper›PMID 30218229›Full record

ArticleClinical oral investigations2019

Mineral density changes in bovine carious dentin after treatment with bioactive dental cements: a comparative micro-CT study.

Aline Borburema Neves, Tamiris Gomes Bergstrom, Andréa Fonseca-Gonçalves, Thais Maria Pires Dos Santos, Ricardo Tadeu Lopes, Aline de Almeida Neves

Abstract read
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Article in Clinical oral investigations, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 28 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Antibacterial mechanism of areca nut essential oils againstFrontiers in cellular and infection microbiology · 2023
    Article
  6. Article
  7. Portland Cement: An Overview as a Root Repair Material.BioMed research international · 2022
    Review
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Aline Borburema NevesDepartment of Pediatric Dentistry and Orthodontics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.ORCID http://orcid.org/0000-0002-0879-9035
Tamiris Gomes BergstromDepartment of Pediatric Dentistry and Orthodontics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Andréa Fonseca-GonçalvesDepartment of Pediatric Dentistry and Orthodontics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Thais Maria Pires Dos SantosLaboratory for Nuclear Instrumentation, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Ricardo Tadeu LopesLaboratory for Nuclear Instrumentation, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Aline de Almeida NevesDepartment of Pediatric Dentistry and Orthodontics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. aline.neves@odonto.ufrj.br.
Universidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the potential of conventional glass ionomer cement (GIC), Biodentine™, MTA, and Portland cement to induce mineral density changes in carious dentin compared to zinc oxide eugenol control cement (ZOE). MATERIALS AND

methodsFifty blocks of bovine root dentin were prepared and a biofilm model using ATCC strains of S.mutans, S.sobrinus, and L.casei was used to promote artificial dentin lesions. After demineralization, the blocks were randomly divided into the five cement groups. Half of the surface of each specimen received the tested material and the other half was covered with wax (control). Samples were stored in phosphate buffered saline solution for 30 days and after that were scanned in a micro-CT with standardized parameters. Dentin mineral density changes were calculated using differences in plot profiles of the exposed and control carious dentin. Friedman's test, followed by Wilcoxon signed-rank test was used with 5% significance.

resultsMean ΔZ values for the cements were 48.63 ± 19.09 for the control (ZOE), 63.31 ± 32.59 for Biodentine™, 114.63 ± 72.92 for GIC, 109.56 ± 66.28 for MTA, and 106.88 ± 66.02 for Portland cement. All cements showed a statistically significant increase in ΔZ values compared to the control, but Biodentine™ values were statistically significantly lower compared to GIC and the other calcium silicate cements.

conclusionsTested materials present potential to induce mineral density changes in carious bovine dentin. MTA, Portland, and GIC showed higher bioactivity potential than Biodentine™. CLINICAL RELEVANCE: Based on minimally invasive concept, materials with remineralization potential can be used to preserve diseased but still repairable dental tissue.

Indexed as

Dental CementsAluminum CompoundsAnimalsCalcium CompoundsCattleDental CariesDentinDrug CombinationsGlass Ionomer CementsMaterials TestingMineralsOxidesRandom AllocationSilicatesX-Ray MicrotomographyAluminum CompoundsCalcium CompoundsDental CementsDrug CombinationsGlass Ionomer CementsMineralsmineral trioxide aggregateOxidesSilicatestricalcium silicateBioactive cementsDentin cariesGlass ionomerMicro-CTMTA

Identifiers

PMID30218229
OpenAlexW2890393809

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.