ArticleCardiovascular engineering and technology2018
In Vitro Validation of 4D Flow MRI for Local Pulse Wave Velocity Estimation.
Article in Cardiovascular engineering and technology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 23 citations in OpenAlex.
- Improved Ultrasonic Local Pulse Wave Velocity Estimation Via Optimal Time Fiduciary Point Combination and Time Delays Fitness.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026Article
- Benchtop Pulse Wave Velocity Measurement From Spatial Wavelength Rather Than Pulse Arrival Time: Feasibility Studies.Journal of biomechanical engineering · 2026Article
- Developing technologies to assess vascular ageing: a roadmap from VascAgeNet.Physiological measurement · 2024Review
- Interpolation time-optimized aortic pulse wave velocity estimation by 4D flow MRI.Scientific reports · 2023Article
- Magnetic Resonance Imaging and Computed Tomography for the Noninvasive Assessment of Arterial Aging: A Review by the VascAgeNet COST Action.Journal of the American Heart Association · 2023Review
- Design of a Patient-Specific Respiratory-Motion-Simulating Platform for In Vitro 4D Flow MRI.Annals of biomedical engineering · 2023Article
- A distributed lumped parameter model of blood flow with fluid-structure interaction.Biomechanics and modeling in mechanobiology · 2021Article
- Assessment of carotid stiffness by measuring carotid pulse wave velocity using a single-slice oblique-sagittal phase-contrast MRI.Magnetic resonance in medicine · 2021Article
- A phantom study comparing radial trajectories for accelerated cardiac 4D flow MRI against a particle imaging velocimetry reference.Magnetic resonance in medicine · 2021Article
- Application of physics-based flow models in cardiovascular medicine: Current practices and challenges.Biophysics reviews · 2021Review
- Evaluation of Plaque Characteristics and Inflammation Using Magnetic Resonance Imaging.Biomedicines · 2021Review
- Assessment of vascular stiffness in the internal carotid artery proximal to the carotid canal in Alzheimer's disease using pulse wave velocity from low rank reconstructed 4D flow MRI.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Article
- Cerebrovascular stiffness and flow dynamics in the presence of amyloid and tau biomarkers.Alzheimer's & dementia (Amsterdam, Netherlands) · 2021Article
- 4D Flow MRI Estimation of Boundary Conditions for Patient Specific Cardiovascular Simulation.Annals of biomedical engineering · 2019Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
purposeArterial stiffness has predictive value for cardiovascular disease (CVD). Local artery stiffness can provide insight on CVD pathology and may be useful for diagnosis and prognosis. However, current methods are invasive, require real-time expertise for measurement, or are limited by arterial region. 4D Flow MRI can non-invasively measure local stiffness by estimating local pulse wave velocity (PWV). This technique can be applied to vascular regions, previously accessible only by invasive stiffness measurement methods. MRI PWV data can also be analyzed post-exam. However, 4D Flow MRI requires validation before it is used in vivo to measure local PWV.
methodsPWV, calculated from 4D Flow MRI and a benchtop experiment, was compared with petersons elastic modulus (PEM) of in vitro models. PEM was calculated using high-speed camera images and pressure transducers. Three transit-time algorithms were analyzed for PWV measurement accuracy and precision.
resultsPWV from 4D Flow MRI and reference benchtop experiments show strong correlation with PEM (R
conclusion4D Flow MRI is a feasible method for estimating local PWV in simple in vitro models and is a viable tool for clinical analysis. In addition, choice in transit-time algorithm depends on flow waveform shape and arterial region. This study strengthens the validity of 4D Flow MRI local PWV measurement in simple models. However, this technique requires validation in more complex models before it is used in vivo.
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