Observational studySupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2019
Modeling symptom drivers of oral intake in long-term head and neck cancer survivors.
Observational study in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- A systematic review of rehabilitation and exercise recommendations in oncology guidelines.CA: a cancer journal for clinicians · 2021Pooled it
- Comparing Functional Outcomes Following TORS With Free Flap Reconstruction Using a Radial Forearm vs. Anterolateral Thigh Flap.Head & neck · 2026Article
- Article
- mEnergy: Development of a Novel mHealth Multi-device Platform for Near Real-time Remote Assessment of Energy Disorders.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2025Article
- Functional Outcomes of Free Flap Reconstruction After TORS in Early-Stage HPV-Positive Oropharyngeal Cancer.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025Article
- Association between objective measures of oral health and salivary gland irradiation with patient-reported outcomes following head and neck radiation therapy.Head & neck · 2024Article
- Improving Prediction of Late Symptoms using LSTM and Patient-reported Outcomes for Head and Neck Cancer Patients.Proceedings. IEEE International Conference on Healthcare Informatics · 2023Article
- THALIS: Human-Machine Analysis of Longitudinal Symptoms in Cancer Therapy.IEEE transactions on visualization and computer graphics · 2022Article
- Predicting late symptoms of head and neck cancer treatment using LSTM and patient reported outcomes.Proceedings. International Database Engineering and Applications Symposium · 2021Article
- Routine Use of Swallowing Outcome Measures Following Head and Neck Cancer in a Multidisciplinary Clinic Setting.International archives of otorhinolaryngology · 2021Article
- Patient-Reported Outcomes-Guided Adaptive Radiation Therapy for Head and Neck Cancer.Frontiers in oncology · 2021Article
- Late and Long-Term Treatment-Related Effects and Survivorship for Head and Neck Cancer Patients.Current treatment options in oncology · 2020Review
- Oral examination findings, taste and smell testing during and following head and neck cancer therapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Article
- Psychometrics of the Functional Oral Intake Scale for Infants.Frontiers in pediatrics · 2019Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
Abstract
purposeThis study examined the relationship between self-reported symptom severity and oral intake in long-term head and neck cancer (HNC) survivors.
methodsAn observational survey study with retrospective chart abstraction was conducted. HNC patients who had completed an MD Anderson Symptom Inventory-Head and Neck (MDASI-HN) questionnaire and also had clinician graded oral intake ratings (Functional Oral Intake Scale [FOIS]) were included. Correlation coefficients were computed. FOIS scores were regressed on MDASI-HN symptom items using stepwise backwards elimination for multivariate models.
resultsOne hundred and fifty-two survey pairings were included in the analysis (median 44 months follow-up, range 7-198). Per FOIS, 28% of survivors maintained a total oral diet with no restrictions, 67% reported a restricted oral diet (without tube), 3% were partially tube-dependent with some oral intake, and 2% were NPO. Of the 22 symptom items, the most severe items in decreasing order were dry mouth, difficulty swallowing\chewing, problems with mucus, tasting food, and choking/coughing. Significant bivariate correlations, after Bonferroni correction for multiple comparisons, were present for 8 of 22 symptoms with FOIS. On multivariate analysis, symptom severity for difficulty swallowing and problems with teeth/gums remained significantly associated with FOIS.
conclusionsOral intake in HNC survivorship is a multidimensional issue and functional outcome that is impacted not only by dysphagia but also by dental status. Symptom drivers of oral intake likely differ in acute survivorship. Nonetheless, these findings highlight the lack of specificity in this end point and also the need for multidisciplinary supportive care to optimize oral intake in survivors.
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