Evidence map›Paper›PMID 30218168›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2019

Factors associated with having an indication for surgery in adult spinal deformity: an international european multicentre study.

S Richner-Wunderlin, A F Mannion, A Vila-Casademunt, F Pellise, M Serra-Burriel, B Seifert, E Aghayev, E Acaroglu, A Alanay, F J S Pérez-Grueso and 3 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Machine learning can predict surgical indication: new clustering model from a large adult spine deformity database.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 4 countries.

S Richner-WunderlinSchulthess Klinik, Zurich, Switzerland. Sarah.Richner-Wunderlin@kws.ch.ORCID 0000-0001-5246-0015
A F MannionSchulthess Klinik, Zurich, Switzerland.
A Vila-CasademuntVall d'Hebron Institute of Research, Barcelona, Spain.
F PelliseVall d'Hebron Institute of Research, Barcelona, Spain.
M Serra-BurrielVall d'Hebron Institute of Research, Barcelona, Spain.
B SeifertDepartment of Biostatistics and Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.
E AghayevSchulthess Klinik, Zurich, Switzerland.
E AcarogluAnkara Spine Center, Ankara, Turkey.
A AlanayAcibadem University, Istanbul, Turkey.
F J S Pérez-GruesoHospital Universitario La Paz, Madrid, Spain.
I ObeidPellegrin University Hospital, Bordeaux, France.
F KleinstückSchulthess Klinik, Zurich, Switzerland.
European Spine Study Group (ESSG)
Schulthess-Klinik · CHVall d'Hebron Institut de Recerca · ESHospital Universitario La Paz · ESUniversity of Zurich · CHAcıbadem University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to evaluate factors that distinguish between patients with adult spinal deformity (ASD) with and without an indication for surgery, irrespective of their final treatment.

methodsBaseline variables (demographics, medical history, outcome measures, coronal, sagittal and neurologic parameters) were evaluated in a multicentre, prospective cohort of patients with ASD. Multivariable analyses were carried out for idiopathic and degenerative patients separately with the dependent variable being "indication for surgery" and baseline parameters as independent variables.

resultsIn total, 342 patients with degenerative ASD and 624 patients with idiopathic ASD were included in the multivariable models. In patients with degenerative ASD, the parameters associated with having an indication for surgery were greater self-rated disability on the Oswestry Disability Index [odds ratio (OR) 1.04, 95% confidence interval (CI) 1.02-1.07] and a lower thoracic kyphosis (OR 0.97 95% CI 0.95-0.99), whereas in patients with idiopathic ASD, it was lower (worse) SRS self-image scores (OR 0.45 95% CI 0.32-0.64), a higher value for the major Cobb angle (OR 1.03 95% CI 1.01-1.05), lower age (OR 0.96 95% CI 0.95-0.98), prior decompression (OR 3.76 95% CI 1.00-14.08), prior infiltration (OR 2.23 95% CI 1.12-4.43), and the presence of rotatory subluxation (OR 1.98 95% CI 1.11-3.54) and sagittal subluxation (OR 4.38 95% CI 1.61-11.95).

conclusionSpecific sets of variables were found to be associated with an indication for surgery in patients with ASD. These should be investigated in relation to patient outcomes for their potential to guide the future development of decision aids in the treatment of ASD. These slides can be retrieved under Electronic Supplementary Material.

Indexed as

Spinal CurvaturesAdultHumansProspective StudiesSeverity of Illness IndexAdult spinal deformityDecision-makingIndication for surgeryMultivariable analysesPrognostic factors

Identifiers

PMID30218168
OpenAlexW2891461909

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.