Evidence map›Paper›PMID 30218157›Full record

ArticleMikrochimica acta2018

Graphene oxide wrapped with gold nanorods as a tag in a SERS based immunoassay for the hepatitis B surface antigen.

Minghuan Liu, Chaohui Zheng, Malin Cui, Xiaoyan Zhang, Da-Peng Yang, Xiansong Wang, Daxiang Cui

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 50 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Minghuan LiuThe Second Affiliated Hospital of Fujian Medical University, Quanzhou, 362000, Fujian Province, China.
Chaohui ZhengThe Second Affiliated Hospital of Fujian Medical University, Quanzhou, 362000, Fujian Province, China.
Malin CuiCollege of Chemical Engineering and Materials Science, Quanzhou Normal University, Fujian Province, China.
Xiaoyan ZhangCollege of Chemical Engineering and Materials Science, Quanzhou Normal University, Fujian Province, China.
Da-Peng YangThe Second Affiliated Hospital of Fujian Medical University, Quanzhou, 362000, Fujian Province, China. yangdp@qztc.edu.cn.
Xiansong WangDepartment of Plastic and Reconstructive Surgery, Shanghai 9th People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China. vincentuis@126.com.
Daxiang CuiInstitute of Nano Biomedicine and Engineering, Shanghai Engineering Research Center for Intelligent Instrument for Diagnosis and Therapy, Department of Instrument Science & Engineering, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China. dxcui@sjtu.edu.cn.
Quanzhou Normal University · CNFujian Medical University · CNShanghai Jiao Tong University · CN

Funding

National Natural Science Foundation of China 81472001
6 · The paper itself

Abstract

A composite consisting of graphene oxide and gold nanorods (GO-GNRs) was designed for the trace determination of hepatitis B surface antigen (HBsAg) using surface enhanced Raman spectroscopy (SERS). GO contains numerous carboxy and hydroxy groups on its surface and therefore can serve as the substrate for decoration with GNRs and for immobilizing antibody against HBsAg. The GNRs (carrying the SERS probe 2-mercaptopyridine) exhibit high SERS activity, and this improves the sensitivity of the biosensor. The antibody on the GO-GNRs binds HBsAg with high specificity, and it results in excellent selectivity. The SERS signal (measured at 1002 cm

Indexed as

Spectrum Analysis, RamanGoldGraphiteHepatitis B Surface AntigensHumansImmunoassayModels, MolecularMolecular ConformationNanotubesOxidesSurface PropertiesGoldGraphiteHepatitis B Surface AntigensOxides2-MercaptopyridineCarbon materialsGold nanomaterialsHepatitis B surface antigenImmunosensorSurface-enhanced Raman scattering tag

Identifiers

PMID30218157
OpenAlexW2890938584

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.