Evidence map›Paper›PMID 30218144›Full record

ReviewInternational journal of colorectal disease2018

Frailty in surgical patients.

Simon J G Richards, Frank A Frizelle, John A Geddes, Tim W Eglinton, Mark B Hampton

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in International journal of colorectal disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04715581 (Effect of Multicomponent Prehabilitation on Early and Long-term Outcomes in Elderly Patients With Frailty After Digestive Surgery for Cancer), which is not on this map. Cited by 59 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04715581 narecruitingnot on this mapstarted 2021, after this paper: background citation

Effect of Multicomponent Prehabilitation on Early and Long-term Outcomes in Elderly Patients With Frailty After Digestive Surgery for Cancer: A Randomized-controlled Study

TypeinterventionalSponsorPeking University First HospitalRan2021 to 2028Enrolled540ConditionsOld Age, Debility, Digestive Cancer, SurgeryArmsPreoperative nutritional optimization, Preoperative exercise training, Postoperative exercise training
3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  13. Management of severe and fulminantJournal of medical microbiology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Simon J G RichardsUniversity of Otago, Christchurch, New Zealand. simon.richards@cdhb.heatlh.nz.ORCID http://orcid.org/0000-0003-0078-6827
Frank A FrizelleUniversity of Otago, Christchurch, New Zealand.
John A GeddesUniversity of Otago, Christchurch, New Zealand.
Tim W EglintonUniversity of Otago, Christchurch, New Zealand.
Mark B HamptonUniversity of Otago, Christchurch, New Zealand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe the current definitions, aetiology, assessment tools and clinical implications of frailty in modern surgical practice.

backgroundFrailty is a critical issue in modern surgical practice due to its association with adverse health events and poor post-operative outcomes. The global population is rapidly ageing resulting in more older patients presenting for surgery. With this, the number of frail patients presenting for surgery is also increasing. Despite the identification of frailty as a significant predictor of poor health outcomes, there is currently no consensus on how to define, measure and diagnose this important syndrome.

methodsRelevant references were identified through keyword searches of the Cochran, MEDLINE and EMbase databases.

resultsDespite the lack of a gold standard operational definition, frailty can be conceptualised as a state of increased vulnerability resulting from a decline in physiological reserve and function across multiple organ systems, such that the ability to withstand stressors is impaired. Multiple studies have shown a strong association between frailty and adverse peri-operative outcomes. Frailty may be assessed using multiple tools; however, the ideal tool for use in a clinical setting has yet to be identified. Despite the association between frailty and adverse outcomes, few interventions have been shown to improve outcomes in these patients.

conclusionFrailty encompasses a group of individuals at high risk of adverse post-operative outcomes. Further work exploring ways to optimally assess and target interventions towards these patients should be the focus of ongoing research.

Indexed as

Frail ElderlyAgedAge FactorsClinical Decision-MakingFemaleFrailtyGeriatric AssessmentHumansMalePatient SelectionPostoperative ComplicationsPredictive Value of TestsRisk AssessmentRisk FactorsSurgical ClearanceSurgical Procedures, OperativeElderlyFrailtyPost-operative outcomesSurgery

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.