Evidence map›Paper›PMID 30218131›Full record

ArticlePsychopharmacology2019

Predicting extinction phenotype to optimize fear reduction.

M H Monfils, H J Lee, N E Keller, R F Roquet, S Quevedo, L Agee, R Cofresi, J Shumake

Abstract read
In one paragraph

Article in Psychopharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. COAddiction biology · 2026
    Article
  2. Associations of COPhysiology & behavior · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. COPhysiology & behavior · 2023
    Article
  9. Reconsolidation and Fear Extinction: An Update.Current topics in behavioral neurosciences · 2023
    Article
  10. Article
  11. COBMC psychiatry · 2022
    Article
  12. The elegant complexity of fear in non-human animals.Emerging topics in life sciences · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Variation in the onset of COScientific reports · 2019
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

M H MonfilsDepartment of Psychology, University of Texas at Austin, Austin, TX, USA. marie.monfils@gmail.com.ORCID http://orcid.org/0000-0001-8971-6651
H J LeeDepartment of Psychology, University of Texas at Austin, Austin, TX, USA.
N E KellerInstitute for Neuroscience, Austin, TX, USA.
R F RoquetDepartment of Psychology, University of Texas at Austin, Austin, TX, USA.
S QuevedoDepartment of Psychology, University of Texas at Austin, Austin, TX, USA.
L AgeeDepartment of Psychology, University of Texas at Austin, Austin, TX, USA.
R CofresiInstitute for Neuroscience, Austin, TX, USA.
J ShumakeDepartment of Psychology, University of Texas at Austin, Austin, TX, USA.

Funding

Neurochemical & Behavioral Correlates of ETOH EffectsT32AA007471 · NIAAA · UNIVERSITY OF TEXAS AUSTIN · PI Kimberly Nixon · 1987 to 2026
$9.2M
Fear memory attenuation: testing reconsolidation-extinction boundariesR01MH091147 · NIMH · UNIVERSITY OF TEXAS AT AUSTIN · PI MONFILS, MARIE H. · 2011 to 2015
$1.9M
National Institute of Mental Health R01MH091147NIAAA NIH HHS T32 AA007471NIMH NIH HHS R01 MH091147
6 · The paper itself

Abstract

Fear conditioning is widely employed to study dysregulations of the fear system. The repeated presentation of a conditioned stimulus in the absence of a reinforcer leads to a decrease in fear responding-a phenomenon known as extinction. From a translational perspective, identifying whether an individual might respond well to extinction prior to intervention could prove important to treatment outcomes. Here, we test the hypothesis that CO

Indexed as

AnimalsBehavior, AnimalCarbon DioxideConditioning, PsychologicalExtinction, PsychologicalFearFreezing Reaction, CatalepticHypothalamic Area, LateralIndividualityMaleMemory, Long-TermOrexinsPhenotypeRatsRats, Sprague-DawleyCarbon DioxideOrexinsCO2Extinction phenotypeFear conditioningFear extinctionIndividual differences

Identifiers

PMID30218131
PMCPMC6391193

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.