Evidence map›Paper›PMID 30218087›Full record

ArticleScientific reports2018

Early identification of esophageal squamous neoplasm by hyperspectral endoscopic imaging.

I-Chen Wu, Hao-Yi Syu, Chun-Ping Jen, Ming-Yen Lu, Yi-Ting Chen, Ming-Tsang Wu, Chie-Tong Kuo, Yu-Yuan Tsai, Hsiang-Chen Wang

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Review
  5. Classification of esophageal cancer by using hyperspectral data.International journal of computer assisted radiology and surgery · 2026
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  9. Precision Imaging for Early Detection of Esophageal Cancer.Bioengineering (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

I-Chen WuDivision of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, No. 100 Shih-Chuan 1st Road, Kaohsiung, 80708, Taiwan.
Hao-Yi SyuGraduate Institute of Opto-Mechatronics, National Chung Cheng University, 168 University Rd., Min-Hsiung, Chia-Yi, 62102, Taiwan.
Chun-Ping JenDepartment of Mechanical Engineering, National Chung Cheng University, 168 University Rd., Min-Hsiung, Chia-Yi, 62102, Taiwan.
Ming-Yen LuDepartment of Materials Science and Engineering, National Tsing Hua University, 101, Sec. 2, Kuang-Fu Road, Hsinchu, 30013, Taiwan.
Yi-Ting ChenDepartment of Pathology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, No. 100 Shih-Chuan 1st Road, Kaohsiung, 80708, Taiwan.
Ming-Tsang WuDepartment of Public Health, Graduate Institute of Clinical Medicine, Research Center for Environmental Medicine, Kaohsiung Medical University, No. 100 Shih-Chuan 1st Road, Kaohsiung, 80708, Taiwan.
Chie-Tong KuoDepartment of Physics, National Sun Yat-sen University, 70 Lienhai Rd., Kaohsiung, 80424, Taiwan.
Yu-Yuan TsaiDepartment of Gastroenterology, Kaohsiung Armed Forces General Hospital, 2, Zhongzheng 1st.Rd., Lingya District, Kaohsiung City, 80284, Taiwan. ytinnz@gmail.com.
Hsiang-Chen WangGraduate Institute of Opto-Mechatronics, National Chung Cheng University, 168 University Rd., Min-Hsiung, Chia-Yi, 62102, Taiwan. hcwang@ccu.edu.tw.ORCID 0000-0003-4107-2062

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esophageal squamous neoplasm presents a spectrum of different diatheses. A precise assessment for individualized treatment depends on the accuracy of the initial diagnosis. Detection relies on comprehensive and accurate white-light, iodine staining, and narrow-band imaging endoscopy. These methods have limitations in addition to its invasive nature and the potential risks related to the method. These limitations include difficulties in precise tumor delineation to enable complete resection, inflammation and malignancy differentiation, and stage determination. The resolution of these problems depends on the surgeon's ability and experience with available technology for visualization and resection. We proposed a method for identifying early esophageal cancerous lesion by endoscopy and hyperspectral endoscopic imaging. Experimental result shows the characteristic spectrum of a normal esophagus, precancerous lesion, canceration, and intraepithelial papillary capillary loop can be identified through principal component score chart. The narrow-band imaging (NBI) image shows remarkable spectral characteristic distribution, and the sensitivity and specificity of the proposed method are higher than those of other methods by ~0.8 and ~0.88, respectively. The proposed method enables the accurate visualization of target organs, it may be useful to capsule endoscope and telemedicine, which requires highly precise images for diagnosis.

Indexed as

Databases, FactualEarly Detection of CancerEndoscopyEsophageal NeoplasmsEsophageal Squamous Cell CarcinomaEsophagusFemaleHumansMaleNarrow Band ImagingSensitivity and Specificity

Identifiers

PMID30218087
PMCPMC6138669

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.