ArticleHypertension research : official journal of the Japanese Society of Hypertension2018
Sex differences and the prognosis of depressive and nondepressive patients with cardiovascular risk factors: the Japan Morning Surge-Home Blood Pressure (J-HOP) study.
Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Sex and Psychosocial Differences in Acute Stress Symptoms Prior to Open-Heart Surgery.International journal of behavioral medicine · 2026Article
- The association between depressive symptoms and masked hypertension in participants with normotension measured at research center.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Mental health problems and hypertension in the elderly: Review from the HOPE Asia Network.Journal of clinical hypertension (Greenwich, Conn.) · 2021Review
- Evaluation of affective temperaments and arterial stiffness in different hypertension phenotypes.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Article
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Abstract
Depression is associated with mortality in patients with cardiovascular risk factors. The frequency and severity of depression and the association between depression and cardiovascular events have sex-specific and ethnic differences. We conducted this study to evaluate the sex-specific difference in the association between depression and cardiovascular prognosis in patients with cardiovascular risk factors. We enrolled 4025 patients (64.7 ± 10.9 years, 53% women, 47% men) with cardiovascular risk factors in the Japan Morning Surge-Home Blood Pressure study. Depressive symptoms were assessed using the Beck Depression Inventory (BDI). The follow-up period was 47 ± 24 months. The primary end points were all-cause mortality and nonfatal cardiovascular events. The BDI scores and the prevalence of depression were significantly higher in women than in men. When a BDI score of 16 was the cutoff, the primary end points in the depression group (n = 217) were significantly higher than those in the nondepression group (n = 1677) among men (adjusted hazard ratio 1.76, 95% confidence interval: 1.17, 2.64; P = 0.007). In women, the primary end points in the depression and nondepression groups were similar when BDI scores of 16, 14, and 10 were the cutoffs. In conclusion, depression defined by a BDI score ≥16 was associated with cardiovascular events in men with cardiovascular risk factors.
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