ArticleThe ISME journal2019
Dynamic genomic architecture of mutualistic cooperation in a wild population of Mesorhizobium.
Article in The ISME journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 44 citations in OpenAlex.
- Causes and consequences of bacterial local adaptation via MGEs in the plant microbiome.The New phytologist · 2026Review
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- Mobile gene clusters and coexpressed plant-rhizobium pathways drive partner quality variation in symbiosis.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Deciphering Soil Keystone Microbial Taxa: Structural Diversity and Co-Occurrence Patterns from Peri-Urban to Urban Landscapes.Microorganisms · 2025Article
- The Hole Truth: Why Do Bumble Bees Rob Flowers More Than Once?Plants (Basel, Switzerland) · 2024Article
- Host-imposed control mechanisms in legume-rhizobia symbiosis.Nature microbiology · 2024Review
- Hosts winnow symbionts with multiple layers of absolute and conditional discrimination mechanisms.Proceedings. Biological sciences · 2023Article
- Article
- Nodulation and Growth Promotion of Chickpea byMicroorganisms · 2022Article
- Evolution of manipulative microbial behaviors in the rhizosphere.Evolutionary applications · 2022Review
- Article
- Phenotypic and genomic signatures of interspecies cooperation and conflict in naturally occurring isolates of a model plant symbiont.Proceedings. Biological sciences · 2022Article
- Why are rhizobial symbiosis genes mobile?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Ecological performance of multifunctional pesticide tolerant strains of Mesorhizobium sp. in chickpea with recommended pendimethalin, ready-mix of pendimethalin and imazethpyr, carbendazim and chlorpyrifos application.Archives of microbiology · 2022Article
- Microbial evolution and transitions along the parasite-mutualist continuum.Nature reviews. Microbiology · 2021Review
- Priority effects alter interaction outcomes in a legume-rhizobium mutualism.Proceedings. Biological sciences · 2021Article
- Specialized metabolic functions of keystone taxa sustain soil microbiome stability.Microbiome · 2021Article
- Repeated gain and loss of a single gene modulates the evolution of vascular plant pathogen lifestyles.Science advances · 2020Article
- Recurrent mutualism breakdown events in a legume rhizobia metapopulation.Proceedings. Biological sciences · 2020Article
- The Non-LegumeFrontiers in plant science · 2019Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Research on mutualism seeks to explain how cooperation can be maintained when uncooperative mutants co-occur with cooperative kin. Gains and losses of the gene modules required for cooperation punctuate symbiont phylogenies and drive lifestyle transitions between cooperative symbionts and uncooperative free-living lineages over evolutionary time. Yet whether uncooperative symbionts commonly evolve from within cooperative symbiont populations or from within distantly related lineages with antagonistic or free-living lifestyles (i.e., third-party mutualism exploiters or parasites), remains controversial. We use genomic data to show that genotypes that differ in the presence or absence of large islands of symbiosis genes are common within a single wild recombining population of Mesorhizobium symbionts isolated from host tissues and are an important source of standing heritable variation in cooperation in this population. In a focal population of Mesorhizobium, uncooperative variants that lack a symbiosis island segregate at 16% frequency in nodules, and genome size and symbiosis gene number are positively correlated with cooperation. This finding contrasts with the genomic architecture of variation in cooperation in other symbiont populations isolated from host tissues in which the islands of genes underlying cooperation are ubiquitous and variation in cooperation is primarily driven by allelic substitution and individual gene gain and loss events. Our study demonstrates that uncooperative mutants within mutualist populations can comprise a significant component of genetic variation in nature, providing biological rationale for models and experiments that seek to explain the maintenance of mutualism in the face of non-cooperators.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.