Evidence map›Paper›PMID 30218014›Full record

ReviewNature reviews. Endocrinology2018

Role of phosphate sensing in bone and mineral metabolism.

Sampada Chande, Clemens Bergwitz

Open access · greenAbstract readReview
In one paragraph

Review in Nature reviews. Endocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed
12.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 197 citations in OpenAlex.

  1. Phosphate homeostasis and endocrine regulators.Pediatric nephrology (Berlin, Germany) · 2026
    Review
  2. The effects of elevated phosphate on the kidney - damaging the gatekeeper.Pflugers Archiv : European journal of physiology · 2026
    Review
  3. Article
  4. Celastrol Attenuates FGF23 Expression in Osteoblasts by Inhibiting STAT3 Activation.Endocrine, metabolic & immune disorders drug targets · 2026
    Article
  5. Article
  6. TGFβ signaling regulates the response of the skeleton to phosphate.bioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Soft tissue calcifications in chronic kidney disease-beyond the vasculature.Pflugers Archiv : European journal of physiology · 2025
    Review
  11. Review
  12. Elevated phosphate levels in CKD - a direct threat for the heart.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Review
  13. Article
  14. Serum Phosphate in the General Population: A Need for Sex-Specific Reference Intervals.The Journal of clinical endocrinology and metabolism · 2025
    Article
  15. Review
  16. Article
  17. Article
  18. Emerging concepts on the FGF23 regulation and activity.Molecular and cellular biochemistry · 2025
    Review
  19. Article
  20. Article

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sampada ChandeSection of Endocrinology and Metabolism, Yale University School of Medicine, New Haven, CT, USA.
Clemens BergwitzSection of Endocrinology and Metabolism, Yale University School of Medicine, New Haven, CT, USA. clemens.bergwitz@yale.edu.
Yale University · US

Funding

Renal Physiology and Phenotyping CoreP30DK079310 · NIDDK · YALE UNIVERSITY · PI SOMLO, STEFAN · 2008 to 2022
$16.8M
DIABETES MELLITUS &DISORDERS OF METABOLISMT32DK007058 · NIDDK · YALE UNIVERSITY · PI SONIA CAPRIO, Kevan C Herold · 1986 to 2026
$9.6M
NIDDK NIH HHS P30 DK079310NIDDK NIH HHS T32 DK007058
6 · The paper itself

Abstract

Inorganic phosphate (P

Indexed as

AnimalsBone and BonesFibroblast Growth Factor-23Fibroblast Growth FactorsGenetic MarkersHomeostasisHumansMiceMineralsMusculoskeletal SystemPhosphatesSensitivity and SpecificitySignal TransductionXenotropic and Polytropic Retrovirus ReceptorFGF23 protein, humanFgf23 protein, mouseFibroblast Growth Factor-23Fibroblast Growth FactorsGenetic MarkersMineralsPhosphatesXenotropic and Polytropic Retrovirus ReceptorXPR1 protein, humanXpr1 protein, mouse

Identifiers

PMID30218014
PMCPMC8607960
OpenAlexW2891550135

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.