Evidence map›Paper›PMID 30218012›Full record

Trial reportScientific reports2018

Randomized trial examining effectiveness of lifestyle intervention in reducing gestational diabetes in high risk Chinese pregnant women in Hong Kong.

Ruth Suk-Mei Chan, Wing-Hung Tam, Ivan Chak-Hang Ho, Macy Wai-Chi Kwan, Liz Sin Li, Mandy Man-Mei Sea, Jean Woo

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02368600 (A Randomized Controlled Trial Examining the Effectiveness of a Lifestyle Intervention in Reducing Gestational Diabetes Mellitus in High Risk Chinese Pregnant Women in Hong Kong), which is not on this map. Cited by 21 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02368600 nacompletednot on this map

A Randomized Controlled Trial Examining the Effectiveness of a Lifestyle Intervention in Reducing Gestational Diabetes Mellitus in High Risk Chinese Pregnant Women in Hong Kong

TypeinterventionalSponsorChinese University of Hong KongRan2015 to 2016Enrolled220ConditionsGestational Diabetes MellitusArmsLifestyle modification program
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ruth Suk-Mei ChanDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China. ruthchansm@cuhk.edu.hk.
Wing-Hung TamDepartment of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong, China.
Ivan Chak-Hang HoDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.
Macy Wai-Chi KwanDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.
Liz Sin LiDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.
Mandy Man-Mei SeaCentre for Nutritional Studies, The Chinese University of Hong Kong, Hong Kong, China.
Jean WooDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.

Funding

Food and Health Bureau of the Government of the Hong Kong Special Administrative Region | Health and Medical Research Fund (HMRF) 12130061
6 · The paper itself

Abstract

Gestational diabetes mellitus (GDM) is of public health concern. This trial examined whether a clinically proven lifestyle modification program (LMP) in early pregnancy was superior to routine antenatal care in improving GDM, maternal and infant outcomes. Chinese pregnant women at risk of GDM (n = 220) were recruited at or before 12-week gestation and randomized to either a LMP group or a routine care control group. Eighty subjects completed a dietitian-led LMP including dietary and exercise components from early pregnancy till 24-week gestation. Data were compared with those of 86 control subjects. Twenty three (26.7%) control subjects and 20 (25.0%) LMP subjects developed GDM (p = 0.798). The proportion of infants born large for gestational age and macrosomia was similar between groups. The LMP group showed a lower proportion of excessive gestational weight gain (GWG). Subgroup analysis suggested that those with higher LMP adherence showed more desirable dietary composition and energy intake, and lower proportion of excessive GWG compared with the low LMP adherence group and the control group. The potential effect of LMP on GDM and other maternal and infant outcomes, in particular GWG, as well as barriers for making lifestyle changes warrant further investigations (ClinicalTrials.gov NCT02368600).

Indexed as

Life StyleAdultDiabetes, GestationalFemaleHong KongHumansOutcome Assessment, Health CarePregnancyRisk

Identifiers

PMID30218012
PMCPMC6138708

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.