Evidence map›Paper›PMID 30217841›Full record

ArticleApplied and environmental microbiology2018

Rapid, Parallel Identification of Catabolism Pathways of Lignin-Derived Aromatic Compounds in Novosphingobium aromaticivorans.

Jacob H Cecil, David C Garcia, Richard J Giannone, Joshua K Michener

Open access · bronzeAbstract readEvaluation Study
In one paragraph

Article in Applied and environmental microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 68 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. UsingACS ES&T engineering · 2026
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  6. mSystems · 2025
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  7. Article
  8. Obtaining PDC and other high-added value products from lignin byJournal of integrative bioinformatics · 2025
    Article
  9. Using DNA affinity purification sequencing (DAP-seq) to identifyMicrobiology resource announcements · 2025
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  10. Article
  11. Article
  12. Laboratory evolution inApplied and environmental microbiology · 2025
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  13. RB-TnSeq barcode abundance data sets forMicrobiology resource announcements · 2025
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  14. Article
  15. Transcriptomic data sets forMicrobiology resource announcements · 2024
    Article
  16. Tools for genetic engineering and gene expression control inApplied and environmental microbiology · 2024
    Article
  17. Article
  18. EngineeringApplied and environmental microbiology · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jacob H CecilBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA.
David C GarciaBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA.
Richard J GiannoneBioEnergy Science Center, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA.
Joshua K MichenerBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA michenerjk@ornl.gov.ORCID 0000-0003-2302-8180
Oak Ridge National Laboratory · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transposon mutagenesis is a powerful technique in microbial genetics for the identification of genes in uncharacterized pathways. Recently, the throughput of transposon mutagenesis techniques has been dramatically increased through the combination of DNA barcoding and high-throughput sequencing. Here, we show that when applied to catabolic pathways, barcoded transposon libraries can be used to distinguish redundant pathways, decompose complex pathways into substituent modules, discriminate between enzyme homologs, and rapidly identify previously hypothetical enzymes in an unbiased genome-scale search. We used this technique to identify two genes,

Indexed as

Metabolic Networks and PathwaysBacterial ProteinsCoumaric AcidsDNA Transposable ElementsEsterasesLigninMetabolic EngineeringMutagenesis, InsertionalSphingomonadaceaeBacterial ProteinsCoumaric AcidsDNA Transposable ElementsEsterasesLigninsinapinic acidaerobic catabolismgeneticsmetabolic engineeringtransposons

Identifiers

PMID30217841
PMCPMC6210112
OpenAlexW2899324516

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.