ArticleApplied and environmental microbiology2018
Metabolic Interactions of a Chain Elongation Microbiome.
Article in Applied and environmental microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 159 citations in OpenAlex.
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- Prokaryotic evolution shapes specialized communities in long term engineered pit mud ecosystem.NPJ biofilms and microbiomes · 2025Article
- Hexanoic Acid Production from Chinese Cabbage Waste Driven by In Situ Lactic Acid Pre-Fermentation: Effect of pH.Applied biochemistry and biotechnology · 2025Article
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- Altering operational conditions during protein fermentation to volatile fatty acids modifies the associated bacterial community.Microbial biotechnology · 2024Article
- Regulation on C2-C8 carboxylic acid biosynthesis from anaerobic COEngineering in life sciences · 2024Article
- Research on the Resource Recovery of Medium-Chain Fatty Acids from Municipal Sludge: Current State and Future Prospects.Microorganisms · 2024Review
- Biosynthesis mechanisms of medium-chain carboxylic acids and alcohols in anaerobic microalgae fermentation regulated by pH conditions.Applied and environmental microbiology · 2024Article
- Liuweizhiji Gegen-Sangshen beverage protects against alcoholic liver disease in mice through the gut microbiota mediated SCFAs/GPR43/GLP-1 pathway.Frontiers in nutrition · 2024Article
- Competitive Reactions during Ethanol Chain Elongation Were Temporarily Suppressed by Increasing Hydrogen Partial Pressure through Methanogenesis Inhibition.Environmental science & technology · 2023Article
- Butanol as a major product during ethanol and acetate chain elongation.Frontiers in bioengineering and biotechnology · 2023Article
- Comparison of metagenomes from fermentation of various agroindustrial residues suggests a common model of community organization.Frontiers in bioengineering and biotechnology · 2023Article
- Metagenomes and Metagenome-Assembled Genomes from Microbiomes Metabolizing Thin Stillage from an Ethanol Biorefinery.Microbiology resource announcements · 2022Article
- Metagenomes and Metagenome-Assembled Genomes from Microbial Communities Fermenting Ultrafiltered Milk Permeate.Microbiology resource announcements · 2022Article
- The Plant-Stress Metabolites, Hexanoic Aacid and Melatonin, Are Potential "Vaccines" for Plant Health Promotion.The plant pathology journal · 2021Review
- Microbial Ecological Mechanism for Long-Term Production of High Concentrations ofApplied and environmental microbiology · 2021Article
- Direct Conversion of Food Waste Extract into Caproate: Metagenomics Assessment of Chain Elongation Process.Microorganisms · 2021Article
- Mixed Acid Fermentation of Carbohydrate-Rich Dairy Manure Hydrolysate.Frontiers in bioengineering and biotechnology · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Carbon chain elongation (CCE), a reaction within the carboxylate platform that elongates short-chain to medium-chain carboxylates by mixed culture, has attracted worldwide interest. The present study provides insights into the microbial diversity and predictive microbial metabolic pathways of a mixed-culture CCE microbiome on the basis of a comparative analysis of the metagenome and metatranscriptome. We found that the microbial structure of an acclimated chain elongation microbiome was a highly similar to that of the original inoculating biogas reactor culture; however, the metabolic activities were completely different, demonstrating the high stability of the microbial structure and flexibility of its functions. Additionally, the fatty acid biosynthesis (FAB) pathway, rather than the well-known reverse β-oxidation (RBO) pathway for CCE, was more active and pivotal, though the FAB pathway had more steps and consumed more ATP, a phenomenon that has rarely been observed in previous CCE studies. A total of 91 draft genomes were reconstructed from the metagenomic reads, of which three were near completion (completeness, >97%) and were assigned to unknown strains of
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.