Evidence map›Paper›PMID 30217193›Full record

Trial reportHealth and quality of life outcomes2018

Physical activity, cardiovascular health, quality of life and blood pressure control in hypertensive subjects: randomized clinical trial.

Victoria Arija, Felipe Villalobos, Roser Pedret, Angels Vinuesa, Dolors Jovani, Gabriel Pascual, Josep Basora

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Health and quality of life outcomes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02767739 (A Randomized Community Trial of Physical Activity Intervention in Primary Healthcare to Improve Cardiovascular Risk Factors and Health-Related Quality of Life in Older Adults), which is not on this map. Cited by 66 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 8 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02767739 nacompletednot on this map

A Randomized Community Trial of Physical Activity Intervention in Primary Healthcare to Improve Cardiovascular Risk Factors and Health-Related Quality of Life in Older Adults

TypeinterventionalSponsorUniversity Rovira i VirgiliRan2011 to 2015Enrolled419ConditionsCardiovascular Diseases, Quality of LifeArmsPhysical, social and cultural activities
3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 8 syntheses or guidelines pooled it, 153 citations in OpenAlex.

  1. Pooled it
  2. Group-delivered interventions for lowering blood pressure in hypertension: a systematic review and meta-analysis.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025
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  7. Walking for hypertension.The Cochrane database of systematic reviews · 2021
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  19. Acute effects of lactate infusion on metabolism, AD biomarkers, and cognition: The LEAN study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Observational
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Victoria ArijaUnitat Suport a la Recerca Reus-Tarragona, Institut d'Investigació en Atenció Primária, IDIAP Jordi Gol (Barcelona), Camí de Riudoms 57, 43202, Reus, Spain. victoria.arija@urv.cat.
Felipe VillalobosFaculty of Medicine and Health Sciences, Universitat Rovira i Virgili, Reus, Tarragona, Spain.
Roser PedretPrimary Health Care Area, Reus, Tarragona, Spain.
Angels VinuesaPrimary Health Care Area, Reus, Tarragona, Spain.
Dolors JovaniPrimary Health Care Area, Reus, Tarragona, Spain.
Gabriel PascualPrimary Health Care Area, Reus, Tarragona, Spain.
Josep BasoraUnitat Suport a la Recerca Reus-Tarragona, Institut d'Investigació en Atenció Primária, IDIAP Jordi Gol (Barcelona), Camí de Riudoms 57, 43202, Reus, Spain.
Institut Català de la Salut · ESGovernment of Catalonia · ESInstitut d'Investigació Sanitària Pere Virgili · ESInstitut Universitari d'Investigació en Atenció Primària Jordi Gol · ESUniversidad Rovira i Virgili · ES

Funding

Departament de Salut, Societat Catalana de Medicina de Família i Comunitària (CAMFIC) and the Associació d'Infermeria Familiar i Comunitària (AIFICC) IV Prize for Research in Innovation Processes of Primary Care and Community Health Care 2011
6 · The paper itself

Abstract

backgroundPhysical activity (PA) promotes cardiovascular health and health related quality of life (HRQoL), although the effect of that on blood pressure (BP) control has rarely been studied in hypertensive subjects. Our aim was to evaluate the effectiveness of a PA intervention programme on cardiovascular disease (CVD) risk, HRQoL and BP control in hypertensive subjects.

methodsA randomized clinical trial, with a PA intervention programme of 9 months duration, comprising a walking group of 120 min/week, supervised, and with socio-cultural activities. Participants were 207 hypertensive subjects (68.2 years, 76.8% women). PA (IPAQ-s), diet, CVD risk, BP, BMI, smoking, and HRQoL (SF-36) were assessed at baseline and at the end of the intervention. Changes in CVD risk and in HRQoL during the intervention was calculated (end-baseline score). Multivariate models were applied.

resultsIn multivariate models, the PA intervention programme, with no modification of the diet, decreased CVD risk (- 1.19 points) and the systolic BP (- 8.68 mmHg), and increased some areas of HRQoL (4.45 to 14.62 points). An increase in the percentage of subjects with controlled BP was observed by the PA programme itself (OR 5.395 to 5.785 according to multivariate models), and by the changes during the intervention in the decrease in CVD risk (OR 0.609) and in the increase in the HRQoL in physical component summary (OR 1.041), role physical (OR 1.010), and bodily pain (OR 1.014), independently of controlled BP at baseline.

conclusionsThis PA intervention programme improved cardiovascular health and HRQoL, and favoured BP control in primary care users with hypertension.

trial registrationClinicaltrials.gov ID NCT02767739 ; Trial registered on May 5th, 2016. Retrospectively registered.

Indexed as

Exercise TherapyQuality of LifeAdultAgedBlood PressureFemaleHealth StatusHealth Status IndicatorsHumansHypertensionMaleMiddle AgedPrimary Health CareTreatment OutcomeWalking

Identifiers

PMID30217193
PMCPMC6137925
OpenAlexW2891010482

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.