Evidence map›Paper›PMID 30217015›Full record

ArticleSensors (Basel, Switzerland)2018

Blood Coagulation Testing Smartphone Platform Using Quartz Crystal Microbalance Dissipation Method.

Jia Yao, Bin Feng, Zhiqi Zhang, Chuanyu Li, Wei Zhang, Zhen Guo, Heming Zhao, Lianqun Zhou

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Parylenes in bioanalytical and cell culture applications.Analytical and bioanalytical chemistry · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jia YaoCAS Key Laboratory of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China. yaojia@sibet.ac.cn.
Bin FengCAS Key Laboratory of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China. fengbincn@foxmail.com.
Zhiqi ZhangCAS Key Laboratory of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China. zhangzhiqi@sibet.ac.cn.
Chuanyu LiCAS Key Laboratory of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China. lichy@sibet.ac.cn.
Wei ZhangCAS Key Laboratory of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China. zhangw@sibet.ac.cn.ORCID 0000-0003-2390-2675
Zhen GuoCAS Key Laboratory of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China. guozhen@sibet.ac.cn.
Heming ZhaoSchool of Electronic and Information Engineering, Soochow University, Suzhou 215006, China. hmzhao@suda.edu.cn.
Lianqun ZhouCAS Key Laboratory of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China. zhoulq@sibet.ac.cn.ORCID 0000-0001-9250-7236
Chinese Academy of Sciences · CNSoochow University · CN

Funding

China Postdoctoral Science Foundation 2016M601890China Postdoctoral Science Foundation 2018T110552Instrument Developing Project of the Chinese Academy of Sciences YZ201638Major Technology Innovation Projects of Jiangsu Province BO2015007National Natural Science Foundation of China 51675517Natural Science Foundation of Jiangsu Province BK20160057Postdoctoral scientific research program of Jiangsu Province 1701010AYouth Innovation Promotion Association of the Chinese Academy of Sciences 2014280Youth Innovation Promotion Association of the Chinese Academy of Sciences 2018360
6 · The paper itself

Abstract

Blood coagulation function monitoring is important for people who are receiving anticoagulation treatment and a portable device is needed by these patients for blood coagulation self-testing. In this paper, a novel smartphone based blood coagulation test platform was proposed. It was developed based on parylene-C coated quartz crystal microbalance (QCM) dissipation measuring and analysis. The parylene-C coating constructed a robust and adhesive surface for fibrin capturing. The dissipation factor was obtained by measuring the frequency response of the sensor. All measured data were sent to a smartphone via Bluetooth for dissipation calculation and blood coagulation results computation. Two major coagulation indexes, activated partial thromboplastin time (APTT) and prothrombin time (PT) were measured on this platform compared with results by a commercial hemostasis system in a clinical laboratory. The measurement results showed that the adjusted R-square (R²) value for APTT and PT measurements were 0.985 and 0.961 respectively. The QCM dissipation method for blood coagulation measurement was reliable and effective and the platform together with the QCM dissipation method was a promising solution for point of care blood coagulation testing.

Indexed as

Quartz Crystal Microbalance TechniquesSmartphoneBlood Coagulation TestsHumansPartial Thromboplastin TimeProthrombin Timeblood coagulationdissipationpoint of care testingquartz crystal microbalancesmartphone

Identifiers

PMID30217015
PMCPMC6164724
OpenAlexW2890215514

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.