ArticleInternational journal of molecular sciences2018
The Degradation Properties of MgO Whiskers/PLLA Composite In Vitro.
Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 29 citations in OpenAlex.
- Harnessing and Optimizing α-TCP for Oral Tissue Engineering and Regenerative Dentistry.International dental journal · 2026Review
- Recent Advances in Whiskers: Properties and Clinical Applications in Dentistry.International journal of nanomedicine · 2024Review
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- Article
- Mechanical Stimulation and Diameter of Fiber Scaffolds Affect the Differentiation of Rabbit Annulus Fibrous Stem Cells.Tissue engineering and regenerative medicine · 2021Article
- Article
- Effect of Magnesium on Dentinogenesis of Human Dental Pulp Cells.International journal of biomaterials · 2021Article
- Biodegradable Poly(Lactic Acid) Nanocomposites for Fused Deposition Modeling 3D Printing.Nanomaterials (Basel, Switzerland) · 2020Review
- Synthesis and Applications of Biopolymer Composites.International journal of molecular sciences · 2019Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, composite films of stearic acid⁻modified magnesium oxide whiskers (Sa⁻w-MgO)/poly-l-lactic acid (PLLA) were prepared through solution casting, and the in vitro degradation properties and cytocompatibility of the composites with different whisker contents were investigated. The results showed that the degradation behavior of the composite samples depended significantly on the whisker content, and the degradation rate increased with the addition of MgO content. Furthermore, the degradation of the composites with higher contents of whiskers was influenced more severely by the hydrophilicity and pH value, leading to more final weight loss, but the decomposition rate decreased gradually. Furthermore, the pH value of the phosphate buffer solution (PBS) was obviously regulated by the dissolution of MgO whiskers through neutralization of the acidic product of PLLA degradation. The cytocompatibility of the composites also increased remarkably, as determined from the cell viability results, and was higher than that of PLLA at the chosen whisker content. This was beneficial for the cell affinity of the material, as it notably led to an enhanced biocompatibility of the PLLA, in favor of promoting cell proliferation, which significantly improved its bioactivity, as well.
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