Evidence map›Paper›PMID 30217012›Full record

ArticleInternational journal of molecular sciences2018

Identification and Characterization of microRNAs during Retinoic Acid-Induced Regeneration of a Molluscan Central Nervous System.

Sarah E Walker, Gaynor E Spencer, Aleksandar Necakov, Robert L Carlone

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sarah E WalkerDepartment of Biological Sciences, Brock University, St. Catharines, ON L2S 3A1, Canada. sw10tn@brocku.ca.
Gaynor E SpencerDepartment of Biological Sciences, Brock University, St. Catharines, ON L2S 3A1, Canada. gspencer@brocku.ca.
Aleksandar NecakovDepartment of Biological Sciences, Brock University, St. Catharines, ON L2S 3A1, Canada. anecakov@brocku.ca.
Robert L CarloneDepartment of Biological Sciences, Brock University, St. Catharines, ON L2S 3A1, Canada. rcarlone@brocku.ca.ORCID 0000-0002-5007-2921
Brock University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retinoic acid (RA) is the biologically active metabolite of vitamin A and has become a well-established factor that induces neurite outgrowth and regeneration in both vertebrates and invertebrates. However, the underlying regulatory mechanisms that may mediate RA-induced neurite sprouting remain unclear. In the past decade, microRNAs have emerged as important regulators of nervous system development and regeneration, and have been shown to contribute to processes such as neurite sprouting. However, few studies have demonstrated the role of miRNAs in RA-induced neurite sprouting. By miRNA sequencing analysis, we identify 482 miRNAs in the regenerating central nervous system (CNS) of the mollusc

Indexed as

AnimalsCentral Nervous SystemGrowth ConesMicroRNAsMolluscaNeuronsTretinoinMicroRNAsTretinoingrowth coneLymnaeamicroRNAneuronal regenerationretinoic acidRNA sequencing

Identifiers

PMID30217012
PMCPMC6163488
OpenAlexW2890603829

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.