Evidence map›Paper›PMID 30217005›Full record

ArticleMolecules (Basel, Switzerland)2018

Sanggenon C Stimulates Osteoblastic Proliferation and Differentiation, Inhibits Osteoclastic Resorption, and Ameliorates Prednisone-Induced Osteoporosis in Zebrafish Model.

Huijuan Wang, Tingting Feng, Donggui Guo, Min Zhang, Lin Chen, Ying Zhou

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Huijuan WangGuizhou Engineering Research Center for the Exploitation and Utilization Technology of Medicine and Food Dual-Use Resources, Guizhou University, Guiyang 550025, China. xuchwhj@163.com.
Tingting FengCollege of Pharmacy, Guizhou University of Chinese Medicine, Guiyang 550025, China. ftt0809@163.com.
Donggui GuoSchool of Food and Pharmaceutical Manufacture Engineering, Guizhou Institute of Technology, Guiyang 550003, China. cbgdg@163.com.
Min ZhangGuizhou Engineering Research Center for the Exploitation and Utilization Technology of Medicine and Food Dual-Use Resources, Guizhou University, Guiyang 550025, China. dream198896@126.com.
Lin ChenGuizhou Engineering Research Center for the Exploitation and Utilization Technology of Medicine and Food Dual-Use Resources, Guizhou University, Guiyang 550025, China. edithcl@sina.com.
Ying ZhouGuizhou Engineering Research Center for the Exploitation and Utilization Technology of Medicine and Food Dual-Use Resources, Guizhou University, Guiyang 550025, China. yzhou@gzu.edu.cn.
Guizhou University · CNGuizhou Institute of Technology · CN

Funding

Guizhou Science and Technology Department [2015]2002-3-4Guizhou Science and Technology Department [2015]7100National Natural Science Foundation of China 81603390Social Plan Project of Guizhou Province [2016]2909
6 · The paper itself

Abstract

Sanggenon C (SC), which is a natural flavonoid found in the stem bark of Cortex Mori, has been discovered to have the antioxidant, anti-inflammatory, and antitumor properties. However, its effect in osteoporosis has not yet been reported. In this research, the effect of SC on the proliferation of MC3T3-E1 cells was evaluated by using the MTT assay. Alkaline phosphatase (ALP) activity and the mRNA expression of

Indexed as

Alkaline PhosphataseAnimalsBenzofuransCell DifferentiationCell LineCell ProliferationChromonesCollagenCore Binding Factor alpha SubunitsDisease Models, AnimalGene Expression RegulationMiceOsteoblastsOsteoclastsOsteoporosisOsteoprotegerinAlkaline PhosphataseBenzofuransChromonesCollagenCore Binding Factor alpha SubunitsOsteoprotegerinPrednisoneRANK Ligandsanggenone CosteoblastosteoclastosteoporosisSanggenon Czebrafish

Identifiers

PMID30217005
PMCPMC6225409
OpenAlexW2890682498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.