Evidence map›Paper›PMID 30216988›Full record

ReviewViruses2018

External Quality Assessment (EQA) for Molecular Diagnostics of Zika Virus: Experiences from an International EQA Programme, 2016⁻2018.

Oliver Donoso Mantke, Elaine McCulloch, Paul S Wallace, Constanze Yue, Sally A Baylis, Matthias Niedrig

Abstract readHistorical ArticleReview
In one paragraph

Review in Viruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Neurodevelopmental Outcomes of Children Following In Utero Exposure to Zika in Nicaragua.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  4. Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Oliver Donoso MantkeQuality Control for Molecular Diagnostics (QCMD), Unit 5, Technology Terrace, Todd Campus, West of Scotland Science Park, Glasgow G20 0XA, UK. OliverDonoso@qcmd.org.
Elaine McCullochQuality Control for Molecular Diagnostics (QCMD), Unit 5, Technology Terrace, Todd Campus, West of Scotland Science Park, Glasgow G20 0XA, UK. ElaineMcCulloch@qcmd.org.
Paul S WallaceQuality Control for Molecular Diagnostics (QCMD), Unit 5, Technology Terrace, Todd Campus, West of Scotland Science Park, Glasgow G20 0XA, UK. PaulWallace@qcmd.org.
Constanze YueDivision of Virology, Paul-Ehrlich-Institut (PEI), Federal Institute for Vaccines and Biomedicines, 63225 Langen, Germany. Constanze.Yue@pei.de.ORCID 0000-0003-3884-5271
Sally A BaylisDivision of Virology, Paul-Ehrlich-Institut (PEI), Federal Institute for Vaccines and Biomedicines, 63225 Langen, Germany. Sally.Baylis@pei.de.
Matthias NiedrigRobert Koch-Institut (RKI), 13353 Berlin, Germany. niedrigm@rki.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quality Control for Molecular Diagnostics (QCMD), an international provider for External Quality Assessment (EQA) programmes, has introduced a programme for molecular diagnostics of Zika virus (ZIKV) in 2016, which has been continuously offered to interested laboratories since that time. The EQA schemes provided from 2016 to 2018 revealed that 86.7% (92/106), 82.4% (89/108), and 88.2% (90/102) of the participating laboratories reported correct results for all samples, respectively in 2016, 2017, and 2018. The review of results indicated a need for improvement concerning analytical sensitivity and specificity of the test methods. Comparison with the outcomes of other EQA initiatives briefly summarized here show that continuous quality assurance is important to improve laboratory performance and to increase preparedness with reliable diagnostic assays for effective patient management, infection and outbreak control.

Indexed as

Disease OutbreaksHistory, 21st CenturyHumansMolecular Diagnostic TechniquesQuality Assurance, Health CareQuality ControlReproducibility of ResultsSensitivity and SpecificityZika VirusZika Virus Infectionassay standardizationemerging arbovirusEQAexternal quality assessmentlaboratory preparednessmolecular diagnosticsmosquito-borne flavivirusoutbreak controlQCMDZika virus

Identifiers

PMID30216988
PMCPMC6163558

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.