Evidence map›Paper›PMID 30216579›Full record

ArticleJournal of veterinary internal medicine2018

Evaluation of point-of-care thoracic ultrasound and NT-proBNP for the diagnosis of congestive heart failure in cats with respiratory distress.

Jessica L Ward, Gregory R Lisciandro, Wendy A Ware, Austin K Viall, Brent D Aona, Kari A Kurtz, Yamir Reina-Doreste, Teresa C DeFrancesco

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 84 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Feline friendly POCUS: how to implement it into your daily practice.Journal of feline medicine and surgery · 2024
    Review
  8. Review
  9. Basic triage in dogs and cats: Part I.The Canadian veterinary journal = La revue veterinaire canadienne · 2024
    Review
  10. Left atrial measurement in lateralThe Canadian veterinary journal = La revue veterinaire canadienne · 2023
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  15. Article
  16. The Feline Cardiomyopathies: 1. General concepts.Journal of feline medicine and surgery · 2021
    Article
  17. The Feline Cardiomyopathies: 2. Hypertrophic cardiomyopathy.Journal of feline medicine and surgery · 2021
    Article
  18. Pathognomonic thoracic radiographic findings are lacking in cats with acute Cytauxzoonosis.Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jessica L WardDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa.ORCID http://orcid.org/0000-0002-9153-7916
Gregory R LisciandroHill Country Veterinary Specialists, Spicewood, Texas.
Wendy A WareDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa.
Austin K ViallDepartment of Veterinary Pathology, College of Veterinary Medicine, Iowa State University, Ames, Iowa.
Brent D AonaDepartment of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina.
Kari A KurtzDepartment of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina.
Yamir Reina-DoresteDepartment of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina.
Teresa C DeFrancescoDepartment of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina.ORCID http://orcid.org/0000-0002-3663-3323
North Carolina State University · USIowa State University · USCarolina Veterinary Specialists · US

Funding

American College of Veterinary Internal Medicine Foundation Cardiology Resident Research grantIowa State University
6 · The paper itself

Abstract

backgroundThe diagnosis of congestive heart failure (CHF) in cats is challenging. Point-of-care (POC) thoracic ultrasound and NT-proBNP testing are emerging tools that may aid in diagnosis. HYPOTHESIS/

objectivesTo assess the diagnostic accuracy of POC lung ultrasound (LUS), focused cardiac ultrasound (FCU), and NT-proBNP in predicting a final diagnosis of CHF. ANIMALS: Fifty-one cats in respiratory distress.

methodsBlood NT-proBNP, LUS, and FCU evaluating left atrial (LA) size and presence of pericardial effusion (PCEFF) were performed in all cats. Lung ultrasound findings including pleural effusion (PLEFF), number of B-lines, and sub-pleural abnormalities were noted. Medical records were evaluated for final diagnosis.

resultsThirty-three of 51 (65%) cats were diagnosed with CHF. Lung ultrasound and blood NT-proBNP were significant predictors of CHF in a multivariate model. The LUS criterion that maximized accuracy for CHF diagnosis was presence of >1 site strongly positive for B-lines (>3 B-lines per site), resulting in sensitivity of 78.8%, specificity of 83.3%, and area under the curve (AUC) of 0.833. Subjective LA enlargement was 97.0% sensitive and 100% specific for CHF (AUC 0.985). Presence of PCEFF also was 100% specific, but only 60.6% sensitive, for CHF (AUC 0.803). A positive blood NT-proBNP test was 93.9% sensitive and 72.2% specific for the diagnosis of CHF (AUC 0.831). CONCLUSIONS AND CLINICAL IMPORTANCE: Point-of-care diagnostic techniques of LUS, FCU, and NT-proBNP are useful to diagnose CHF in cats with respiratory distress.

Indexed as

Point-of-Care SystemsAnimalsBiomarkersCat DiseasesCatsEchocardiographyFalse Negative ReactionsFalse Positive ReactionsFemaleHeart FailureMaleNatriuretic Peptide, BrainPeptide FragmentsRetrospective StudiesBiomarkersNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)biomarkerB-linescardiacfelinelungpoint-of-carerespiratory

Identifiers

PMID30216579
PMCPMC6189386
OpenAlexW2890447633

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.