Evidence map›Paper›PMID 30216528›Full record

ArticleMagnetic resonance in medicine2019

Calibration of methylene-referenced lipid-dissolved xenon frequency for absolute MR temperature measurements.

Michael A Antonacci, Le Zhang, Simone Degan, Detlev Erdmann, Rosa T Branca

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Preclinical MRI Using HyperpolarizedMolecules (Basel, Switzerland) · 2022
    Review
  3. An open-source, low-cost NMR spectrometer operating in the mT field regime.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2021
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Michael A AntonacciDepartment of Physics and Astronomy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Le ZhangBiomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Simone DeganCenter for Molecular and Biomolecular Imaging, Department of Radiology and Dermatology, Duke University, Durham, North Carolina.
Detlev ErdmannDivision of Plastic, Reconstructive, Maxillofacial and Oral Surgery, Duke University Medical Center, Durham, North Carolina.
Rosa T BrancaDepartment of Physics and Astronomy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
University of North Carolina at Chapel Hill · USDuke Medical Center · USDuke University · USImaging Center · US

Funding

Sensitive and Specific detection of BAT Tissue and Activity by Magnetic Resonance with Hyperpolarized Xe-129R01DK108231 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BRANCA, ROSA TAMARA · 2015 to 2019
$1.6M
NIDDK NIH HHS R01 DK108231NIH HHS R01 DK108231
6 · The paper itself

Abstract

purposeAbsolute MR temperature measurements are currently difficult because they require precalibration procedures specific for tissue types and conditions. Reference of the lipid-dissolved

methodsNeat triglycerides, vegetable oils, and samples of freshly excised human and rodent adipose tissue (AT) are prepared under

resultsAlthough rLDX CS shows a dependence on lipid composition, in human and rodent AT samples the rLDX shows consistent CS values with a similar temperature dependence (-0.2058 ± 0.0010) ppm/°C × T (°C) + (200.15 ± 0.03) ppm, enabling absolute temperature measurements with an accuracy of 0.3°C. Methylene-referenced water CS values present variations of up to 4°C, even under well-controlled conditions.

conclusionsThe rLDX can be used to obtain accurate absolute temperature measurements in AT, opening new opportunities for hyperpolarized

Indexed as

Magnetic Resonance ImagingXenonAdipose TissueAnimalsCalibrationHumansLipidsPlant OilsProtonsRatsReference ValuesReproducibility of ResultsTemperatureTriglyceridesWaterLipidsPlant OilsProtonsTriglyceridesWaterXenonbrown adipose tissuechemical shiftmagnetic resonance spectroscopyMR thermometryxenon spectroscopy

Identifiers

PMID30216528
PMCPMC8127983
OpenAlexW2890803051

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.