ReviewParasite immunology2019
Parasites and allergy: Observations from Africa.
Review in Parasite immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- The human immunome in the post-schistosomiasis mass drug administration era.PLoS neglected tropical diseases · 2026Review
- Article
- Food Allergies and Parasites in Children.Foods (Basel, Switzerland) · 2023Review
- Multiple overlapping risk factors for childhood wheeze among children in Benin.European journal of medical research · 2022Article
- Association between allergic sensitization and intestinal parasite infection in schoolchildren in Gqeberha, South Africa.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2022Article
- Lack of Consistent Association between Asthma, Allergic Diseases, and Intestinal Helminth Infection in School-Aged Children in the Province of Bengo, Angola.International journal of environmental research and public health · 2021Article
- Immunomodulation and Immune Escape Strategies of Gastrointestinal Helminths and Schistosomes.Frontiers in immunology · 2020Review
- Risk factors for asthma among schoolchildren who participated in a case-control study in urban Uganda.eLife · 2019Article
- Trickle infection and immunity to Trichuris muris.PLoS pathogens · 2019Article
- Parasites and allergy: Observations from Africa.Parasite immunology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Population studies from the African continent have observed a marked increase in the prevalence of allergy-related diseases over the past few decades, but the cause of this rise is not fully understood. The most investigated potential risk factor has been the relationship between exposure to helminths and allergy-related outcomes. Immunologically, parallels exist between responses to helminths and to allergens as both are associated with elevated levels of immunoglobulin E, increased numbers of T helper 2 cells and other immune cells. However, epidemiological studies from the African continent have found inconsistent results. In this review, observations from population studies carried out in Africa over the last decade that focus on the relationship between helminth infections and allergy-related outcomes are examined. How these findings advance our understanding of the complex interactions between helminths and allergies at the population level is also explored as well as some of the underlying immune mechanisms involved. This knowledge is important for better diagnosis, treatment and prevention of allergy-related diseases and has wider global significance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.