Evidence map›Paper›PMID 30216465›Full record

ArticleMedical physics2018

Use of a laser-guided collimation system to perform direct kilovoltage x-ray spectra measurements on a linear accelerator onboard imager.

Zachary Grelewicz, Andrew H Belcher, Rodney D Wiersma

Open access · greenAbstract read
In one paragraph

Article in Medical physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Zachary GrelewiczDepartment of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, 60637-1470, USA.
Andrew H BelcherDepartment of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, 60637-1470, USA.
Rodney D WiersmaDepartment of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, 60637-1470, USA.
University of Chicago · US

Funding

RESEARCH TRAINING IN MEDICAL PHYSICST32EB002103 · NIBIB · UNIVERSITY OF CHICAGO · PI ARMATO, SAMUEL G. · 2003 to 2019
$4.7M
American Cancer Society RSG-13-313-01-CCENIBIB NIH HHSNIBIB NIH HHS T32 EB002103NIH HHS T32-EB002103
6 · The paper itself

Abstract

purposeThe increased use of image-guided radiation therapy (IGRT) has led to increased use of kV on board imaging (OBI) devices. At present, directly measured OBI beam quality data have only been reported in terms of half-value layers (HVL). However, the HVL metric alone does not give the full OBI energy spectra as needed for accurate beam modeling. Although direct kV spectrometer devices exist they typically suffer from detector pile-up when used with OBI sources. We therefore present, for the first time, a novel laser-guided collimation system that allows direct measurement of the full energy spectrum for clinical OBI systems.

methodsSeveral clinically relevant spectra (80, 100, and 125 kVp), with and without the half bow-tie filter, were measured using a thermoelectric cooled cadmium telluride (CdTe) detector paired with a multichannel analyzer. To prevent detector saturation, the photon flux at the detector was reduced by use of an in-house designed laser-guided collimation system. After applying energy bin corrections, direct spectroscopic measurements were compared to Monte Carlo (MC) simulated spectra in order to verify accuracy of collected data. Both percent depth dose (PDD) curves and digitally reconstructed radiographs (DRR) were compared using the measured vs MC spectra.

resultsMeasured and MC spectra agree with RMSD between 1.96% and 3.29%. PDD curves generated from the measured and MC spectra were found to match except for in the small buildup region, with an overall match for the six beams ranging between 0.3% and 2.7% RMSD. DRRs matched well with a maximum difference in contrast of 1.1% and RMSD of 0.46% contrast for various materials in DRRs.

conclusionsThe use of a laser-guided collimation system provided a method for quickly obtaining highly accurate kV spectrum data from OBI sources. For kV dose or DRR calculation, it was found that both spectra produced similar results.

Indexed as

LasersParticle AcceleratorsMonte Carlo MethodRadiotherapy, Image-GuidedSpectrum Analysiscollimationenergy spectrumkV imaginglaser alignmentlinear accelerator (linac)onboard imaging (OBI)x-ray source

Identifiers

PMID30216465
PMCPMC6234071
OpenAlexW2891204486

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.