Evidence map›Paper›PMID 30216416›Full record

ArticleCancer2018

The relationship between household income and patient-reported symptom distress and quality of life in children with advanced cancer: A report from the PediQUEST study.

Maya F Ilowite, Hasan Al-Sayegh, Clement Ma, Veronica Dussel, Abby R Rosenberg, Chris Feudtner, Tammy I Kang, Joanne Wolfe, Kira Bona

Open access · bronzeAbstract read
In one paragraph

Article in Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 65 citations in OpenAlex.

  1. Associations of Age, Gender, and Family Income with Quality of Life in Children With Advanced Cancer.Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses
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  13. Exploring core symptoms and interrelationships among symptoms in children with acute leukemia during chemotherapy: A network analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 2 countries.

Maya F IlowiteDepartment of Pediatric Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.
Hasan Al-SayeghDepartment of Pediatric Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.
Clement MaDepartment of Pediatric Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.
Veronica DusselDepartment of Pediatric Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.
Abby R RosenbergSeattle Children's Hospital Cancer and Blood Disorders Center, Seattle, Washington.
Chris FeudtnerThe Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Tammy I KangSection of Palliative Care, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.
Joanne WolfeDepartment of Pediatric Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.
Kira BonaDepartment of Pediatric Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.
Dana-Farber/Boston Children's Cancer and Blood Disorders Center · USDana-Farber Cancer Institute · USHarvard University · USInstituto de Efectividad Clínica y Sanitaria · ARSeattle Children's Hospital · USTexas Children's Hospital · USUniversity of Pennsylvania · US

Funding

Material Hardship as a Targetable Measure of Poverty in Pediatric CancerK07CA211847 · NCI · DANA-FARBER CANCER INST · PI BONA, KIRA O. · 2016 to 2021
$731k
Improving Care for Children with Advanced CancerK07CA096746 · NCI · DANA-FARBER CANCER INSTITUTE · PI WOLFE, JOANNE · 2002 to 2006
$678k
NCI NIH HHS K07 CA096746NCI NIH HHS K07 CA211847
6 · The paper itself

Abstract

backgroundChildren with advanced cancer experience high symptom distress, which negatively impacts their health-related quality of life (HRQOL). To the authors' knowledge, the relationship between income and symptom distress and HRQOL is not well described.

methodsThe Pediatric Quality of Life and Symptoms Technology (PediQUEST) multisite clinical trial evaluated an electronic patient-reported outcome system to describe symptom distress and HRQOL in children with advanced cancer via repeated surveys. The authors performed a secondary analysis of PediQUEST data for those children with available parent-reported household income (dichotomized at 200% of the Federal Poverty Level and categorized as low income [<$50,000/year] or high income [≥$50,000/year]). The prevalence of the 5 most commonly reported physical and psychological symptoms was compared between groups. Multivariable generalized estimating equation models were used to test the association between household income and symptom distress and HRQOL.

resultsA total of 78 children were included in the analyses: 56 (72%) in the high-income group and 22 (28%) in the low-income group. Low-income children were more likely to report pain than high-income children (64% vs 42%; P=.02). In multivariable models, children from low-income families demonstrated a uniform trend toward higher total (β

conclusionsIn this cohort of children with advanced cancer, children from low-income families were found to experience higher symptom burden and worse QOL.

Indexed as

Quality of LifeAdolescentCancer PainChildChild, PreschoolCost of IllnessDisease ProgressionFamily CharacteristicsFemaleHealth Status DisparitiesHumansIncomeMaleNeoplasmsPatient Reported Outcome MeasuresPovertydisparity in symptom burdenpatient-reported outcomespediatric advanced cancerpediatric palliative carePediatric Quality of Life and Symptoms Technology (PediQUEST)

Identifiers

PMID30216416
PMCPMC6561342
OpenAlexW2890185787

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.