ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2019
Financial Impact of Anastomotic Leakage in Colorectal Surgery.
Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05810207 (The External Validation of a Machine Learning Model Predicting Anastomotic Leakage Intraoperatively in Patients Undergoing a Colorectal Resection - A1Check Study), which is not on this map. Cited by 34 papers, 5 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The External Validation of a Machine Learning Model Predicting Anastomotic Leakage Intraoperatively in Patients Undergoing a Colorectal Resection - A1Check Study: Protocol for a Multicenter Observational Study
Who cites it
34 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- The impact of the number of stapler firings on anastomotic leakage in minimally invasive rectal surgery: risk factor or technical marker of complexity? A systematic review, meta‑analysis, and metaregression.Techniques in coloproctology · 2026Pooled it
- Current evidence on powered versus manual circular staplers in colorectal surgery: a systematic review and meta-analysis.International journal of colorectal disease · 2025Pooled it
- The economic impact of anastomotic leakage after colorectal surgery: a systematic review.Techniques in coloproctology · 2024Pooled it
- Assessment of intraoperative use of indocyanine green fluorescence imaging on the incidence of anastomotic leakage after rectal cancer surgery: a PRISMA-compliant systematic review and meta-analysis.Techniques in coloproctology · 2021Pooled it
- Identification and economic burden of main adverse events of nerve injuries caused by regional anesthesia: a systematic review.Brazilian journal of anesthesiology (Elsevier)Pooled it
- Ultrasound-Guided Pudendal Nerve Block in Patients Undergoing Open Hemorrhoidectomy: A Post-Hoc Cost-Effectiveness Analysis from a Double-Blind Randomized Controlled Trial.ClinicoEconomics and outcomes research : CEOR · 2021Trial
- Early Post-Operative Diagnosis of Anastomotic Leak by Local Electrophysiological Parameters: Multicenter Pilot Study.Diagnostics (Basel, Switzerland) · 2026Article
- Costs associated with anastomotic leak after left-sided colorectal surgery: retrospective real-world study in England.BJS open · 2026Article
- Non-Thermal Atmospheric Pressure Plasma as an Adjunct to Intestinal Anastomosis: A Pilot Study on Preventing Anastomotic Leaks.Life (Basel, Switzerland) · 2024Article
- Analysis of decision-making factors for defunctioning ileostomy after rectal cancer surgery and their impact on perioperative recovery: a retrospective study of 1082 patients.Surgical endoscopy · 2024Article
- Incidence of anastomotic leakage using powered circular staplers versus manual circular staplers for left colorectal anastomosis: a cost-effectiveness analysis.Techniques in coloproctology · 2024Observational
- Clinical and computational development of a patient-calibrated ICGFA bowel transection recommender.Surgical endoscopy · 2024Article
- Impact of standardising indocyanine green fluorescence angiography technique for visual and quantitative interpretation on interuser variability in colorectal surgery.Surgical endoscopy · 2024Article
- Assessment of gastric pouch blood supply with indocyanine green fluorescence in conversional and revisional bariatric surgery: a prospective comparative study.Scientific reports · 2023Article
- A nationwide population-based study on the clinical and economic burden of anastomotic leakage in colorectal surgery.Langenbeck's archives of surgery · 2023Article
- Deconstructing mastery in colorectal fluorescence angiography interpretation.Surgical endoscopy · 2022Article
- Development of a warning score for early detection of colorectal anastomotic leakage: Hype or hope?World journal of gastrointestinal surgery · 2022Article
- Anastomotic Rings and Inflammation Values as Biomarkers for Leakage of Stapled Circular Colorectal Anastomoses.Diagnostics (Basel, Switzerland) · 2022Article
- Review
- The Effects of Anastomotic Leaks on the Net Revenue from Colon Surgery.International journal of environmental research and public health · 2022Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnastomotic leakage after colorectal surgery is a complication that requires additional treatments strongly affecting the economic outcomes. We evaluated the use of resources and the economic burden associated with anastomotic leaks following colorectal surgery.
methodsBetween January 2015 and December 2016, we retrospectively evaluated patients who underwent colorectal surgery with primary anastomosis. We compared the medical resource utilization and the DRG-based reimbursement of cases with uncomplicated surgery and cases complicated by anastomotic leakage.
resultsOf the 95 patients included in the study, 87 (92%) presented an uneventful postoperative course and 8 patients (8%) developed an anastomotic leakage requiring surgery. The statistical analysis showed no significant differences in terms of demographics, risks factor, and operative results, except the length of hospital stay (9.7 vs. 29.1 days, p < 0.01). The cost for 87 uncomplicated cases was 1,535,297 EUR (average cost of 17,647 EUR), whereas the cost of the 8 patients with anastomotic leakage was 575,822 EUR (average cost of 71,978 EUR) (p < 0.01). For each patient, the hospital had 542 EUR profit in the uncomplicated group and a 12,181 EUR loss in the anastomotic leakage group (p < 0.01). The multiple R-squared line regression analysis showed that factors independently related to costs were age (p = 0.05) and length of hospital stay (p = 0.01).
conclusionsIn terms of economic impact, the occurrence of an anastomotic leakage has a large negative influence on medical resource utilization, so that, despite the complication-related increase of DRG-reimbursement, every complicated case represents a financial burden for the hospital.
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