Evidence map›Paper›PMID 30215055›Full record

ArticleJSM dental surgery2017

High Frequency Acceleration: A New Tool for Alveolar Bone Regeneration.

M Alikhani, C Sangsuwon, S Alansari, J M Nervina, C C Teixeira

Open access · greenAbstract read
In one paragraph

Article in JSM dental surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Alveolar Bone Regeneration: Smart Biomaterials and Physical Stimulation.Journal of biomedical materials research. Part B, Applied biomaterials · 2026
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

M AlikhaniConsortium for Translational Orthodontic Research, New York University College of Dentistry, USA.
C SangsuwonConsortium for Translational Orthodontic Research, New York University College of Dentistry, USA.
S AlansariConsortium for Translational Orthodontic Research, New York University College of Dentistry, USA.
J M NervinaConsortium for Translational Orthodontic Research, New York University College of Dentistry, USA.
C C TeixeiraConsortium for Translational Orthodontic Research, New York University College of Dentistry, USA.
New York University · US

Funding

High Frequency Acceleration to Restore Alveolar BoneR43DE025518 · NIDCR · PROPEL ORTHODONTICS, LLC · PI WAY, BRYCE · 2015 to 2015
$224k
NIDCR NIH HHS R43 DE025518
6 · The paper itself

Abstract

introductionA common problem in clinical dentistry is the significant and rapid bone loss that occurs after periodontitis, osteoporosis, tooth extractions, lack of function, or any other pathologic condition that target the alveolar bone. Currently there is no stable solution for the long-term preservation or rehabilitation of alveolar bone. In this article, we review the latest concepts on bone response to mechanical stimulation, and summarize the results of our studies on the effect of high frequency acceleration (HFA) on healthy alveolar bone and on healing alveolar bone after extractions.

methodsIn both studies, we used adult Sprague Dawley rats to test the response of alveolar bone to different frequencies and accelerations applied to the maxillary molars.

resultsOnce we determined which parameters of HFA induced a higher osteogenic response, we tested the effect of this mechanical stimulation during bone healing after molar extraction. Our studies strongly show that HFA can stimulate bone formation in the healthy alveolar bone surrounding the tooth/point of application as well as the distant bone surrounding the neighboring teeth. When HFA was applied to the second molar, after extraction of the third molar, it accelerated bone healing and prevented alveolar bone resorption in and around the extraction socket.

conclusionHFA is a noninvasive safe treatment that can be used to prevent alveolar bone loss, accelerate bone healing and to improve the quality and quantity of alveolar bone under both physiological and pathological conditions.

Indexed as

AccelerationBone preservationExtractionHigh frequencyNoninvasive therapyOsteoporosisVibration

Identifiers

PMID30215055
PMCPMC6133260
OpenAlexW2980616921

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.