ArticleAnnals of hepato-biliary-pancreatic surgery2018
Predictors of post-hepatectomy liver failure in patients undergoing extensive liver resections for hepatocellular carcinoma.
Article in Annals of hepato-biliary-pancreatic surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A Systematic Review and Meta-Analysis of Oncologic Liver Resections in Low- and Middle-Income Countries: Opportunities to Improve Evidence and Outcomes.Journal of surgical oncology · 2025Pooled it
- Meta-analysis of Prognostic Factors for Overall Survival Among Resected Patients with Spontaneous Ruptured Hepatocellular Carcinoma.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023Pooled it
- Immediate prediction and early intervention for post-hepatectomy liver failure: external validation of the modified Rem-ALPlat index.International journal of clinical oncology · 2026Article
- Additive value of oncological resectability criteria for predicting post-hepatectomy liver failure in hepatocellular carcinoma.Updates in surgery · 2026Article
- Preoperative evaluation of post-hepatectomy liver failure in hepatocellular carcinoma based on gadoxetic acid-enhanced MRI.Frontiers in oncology · 2026Article
- A comparative study of machine learning models predicting post-hepatectomy liver failure: Enhancing risk estimation in over 25,000 National Surgical Quality Improvement Program patients.Annals of hepato-biliary-pancreatic surgery · 2025Article
- Overall survival is comparable between percutaneous radiofrequency ablation and liver resection as first-line therapies for solitary 3-5 cm hepatocellular carcinoma.Langenbeck's archives of surgery · 2025Article
- Outcomes after laparoscopic or open liver resection for nonalcoholic fatty liver disease-associated hepatocellular carcinoma: a propensity score-matching study.Surgical endoscopy · 2024Article
- E-AHPBA-ESSO-ESSR Innsbruck consensus guidelines for preoperative liver function assessment before hepatectomy.The British journal of surgery · 2023Article
- Impact of the Intermittent Pringle Maneuver for Predicting Post-hepatectomy Liver Failure: A Cohort Study of 597 Consecutive Patients.World journal of surgery · 2023Article
- A radiomics model based on preoperative gadoxetic acid-enhanced magnetic resonance imaging for predicting post-hepatectomy liver failure in patients with hepatocellular carcinoma.Frontiers in oncology · 2023Article
- A comprehensive preoperative predictive score for post-hepatectomy liver failure after hepatocellular carcinoma resection based on patient comorbidities, tumor burden, and liver function: the CTF score.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022Article
- Outcomes of patients with post-hepatectomy hypophosphatemia: A narrative review.World journal of hepatology · 2022Review
- Individualized risk estimation for postoperative pulmonary complications after hepatectomy based on perioperative variables.World journal of gastrointestinal surgery · 2022Article
- Machine learning prediction model for post- hepatectomy liver failure in hepatocellular carcinoma: A multicenter study.Frontiers in oncology · 2022Article
- A Novel Nomogram for Prediction of Post-Hepatectomy Liver Failure in Patients with Resectable Hepatocellular Carcinoma: A Multicenter Study.Journal of hepatocellular carcinoma · 2022Article
- Diabetes mellitus and postoperative blood glucose value help predict posthepatectomy liver failure in patients with hepatocellular carcinoma.Journal of gastrointestinal oncology · 2021Article
- A novel preoperative predictive model of 90-day mortality after liver resection for huge hepatocellular carcinoma.Annals of translational medicine · 2021Article
- Prediction of Post-hepatectomy Liver Failure in Patients With Hepatocellular Carcinoma Based on Radiomics Using Gd-EOB-DTPA-Enhanced MRI: The Liver Failure Model.Frontiers in oncology · 2021Article
- Early Prediction of Post-hepatectomy Liver Failure in Patients Undergoing Major Hepatectomy Using a PHLF Prognostic Nomogram.World journal of surgery · 2020Article
Corrections and comments
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUNDS/
aimsTo determine the prevalence of post-hepatectomy liver failure/insufficiency (PHLF/I) in patients undergoing extensive hepatic resections for hepatocellular carcinoma (HCC) and to assess the predictive value of preoperative factors for post-hepatectomy liver failure or insufficiency (PHLF/I).
methodsA retrospective review of patients who underwent liver resections for HCC between 2001 and 2013 was conducted. Preoperative parameters were assessed and analyzed for their predictive value of PHLF/I. Definitions used included the 50-50, International Study Group of Liver Surgery (ISGLS) and Memorial Sloan Kettering Cancer Centre (MSKCC) criteria.
resultsAmong the 848 patients who underwent liver resections for HCC between 2001 and 2013, 157 underwent right hepatectomy (RH) and extended right hepatectomy (ERH). The prevalence of PHLF/I was 7%, 41% and 28% based on the 50-50, ISGLS and MSKCC criteria, respectively. There were no significant differences in PHLF/I between RH and ERH. Model for End-Stage Liver Disease (MELD) score and bilirubin were the strongest independent predictors of PHLF/I based on the 50-50 and ISGLS/MSKCC criteria, respectively. Predictive models were developed for each of the criteria with multiple logistic regression.
conclusionsMELD score, bilirubin, alpha-fetoprotein and platelet count showed significant predictive value for PHLF/I (all
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