ArticleClinical neurophysiology practice2018
Method-of-limits; Cold and warm perception thresholds at proximal and distal body regions.
Article in Clinical neurophysiology practice, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 28 citations in OpenAlex.
- Normative Reference Values for Vibration, Warm and Cold Perception Thresholds in an Indian Population Using the Vibrasense + T Device.Annals of neurosciences · 2026Article
- Foot dorsum thermal quantitative sensory testing thresholds in healthy Vietnamese adults: Reference data.Clinical neurophysiology practice · 2026Article
- Sense-checking the approach to quantitative sensory testing to detect chemotherapy-induced peripheral neuropathy.PloS one · 2025Article
- The impact of pregnancy and childbirth on pelvic sensation: a prospective cohort study.Scientific reports · 2023Article
- Multidimensional pain phenotypes after Traumatic Brain Injury.Frontiers in pain research (Lausanne, Switzerland) · 2022Article
- Age Differences in Multimodal Quantitative Sensory Testing and Associations With Brain Volume.Innovation in aging · 2021Article
- Can within-subject comparisons of thermal thresholds be used for diagnostic purposes?Clinical neurophysiology practice · 2021Article
- A test-retest reliability study of assessing small cutaneous fibers by measuring current perception threshold with pin electrodes.PloS one · 2020Article
- Concurrent validity of a low-cost and time-efficient clinical sensory test battery to evaluate somatosensory dysfunction.European journal of pain (London, England) · 2019Article
- Assessment of Neuropathy by Temperature Threshold Testing in Type 2 Diabetes Mellitus.International journal of applied & basic medical researchArticle
- Inter-trial Variation in the Sensitivity of Thermal Threshold Testing for the Diagnosis of Neuropathy in Type 2 Diabetes Mellitus.International journal of applied & basic medical researchArticle
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThermal quantitative sensory testing with the 'Method-of-Limits' is an established rationale for detection of small nerve fiber dysfunction, but adequate reference values are crucial for such evaluations, regardless of the underlying cause. This study assessed reference data for cold- (CPT) and warm- (WPT) perception thresholds at both proximal and distal sites in eight body regions of the lower and upper extremities, all determined within the same test session for each subject.
methodsSeventy-five healthy subjects (aged 16-72 years) were tested according to the method-of-limit for CPT and WPT at the dorsum of the foot, the medial and lateral lower leg, the ventral thigh, the thenar eminence, the radial and ulnar part of the lower arm, and the anterior deltoid part of the upper arm.
resultsOverall, thermal perception thresholds (TPT) varied with test location, but were higher in the lower than in the upper part of the body, also WPT were generally higher than CPT. TPT at the dorsum foot highly correlated with age, while inconsistent correlations were noted between TPT and age or height at other tested locations.
conclusionThis study describes for the first time reference values at eight defined body regions, at both proximal and distal sites. SIGNIFICANCE: The report enables refined evaluations of general small nerve fiber function, as assessed by quantitative thermal sensory testing with the Method-of-Limits.
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