ReviewClinical neurophysiology practice2017
Post-hypoxic myoclonus: Differentiating benign and malignant etiologies in diagnosis and prognosis.
Review in Clinical neurophysiology practice, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 41 citations in OpenAlex.
- Status epilepticus as a novel etiology of Lance-Adams syndrome: a case report.Epilepsy & behavior reports · 2026Article
- Article
- Lance-Adams Syndrome: An Updated Review of a Rare Post-Hypoxic Complication.Tremor and other hyperkinetic movements (New York, N.Y.) · 2025Review
- Lance-Adams syndrome or chronic post-hypoxic myoclonus in adults: a systematic literature review.Brain communications · 2025Review
- Optimizing brain protection after cardiac arrest: advanced strategies and best practices.Interface focus · 2024Review
- Article
- Myoclonus: Differential diagnosis and current management.Epilepsia open · 2024Review
- Post hypoxic myoclonus: A tale of two minds.Epilepsy & behavior reports · 2023Article
- A Rare Case of Lance-Adams Syndrome: Status Post-Successful Cardiopulmonary Resuscitation.Cureus · 2022Article
- Lance Adams syndrome: two cases report and literature review.The Journal of international medical research · 2022Review
- Lance Adams Syndrome: A Rare Case Presentation of Myoclonus From Chronic Hypoxia Secondary to COVID-19 Infection.Cureus · 2021Article
- An Exploration of the Neural Network of Lance-Adams Syndrome: a Case Report.Brain & NeuroRehabilitation · 2021Article
- Myoclonus in Patients With Coronavirus Disease 2019: A Multicenter Case Series.Critical care medicine · 2020Article
- Neurologic prognostication after resuscitation from cardiac arrest.Journal of the American College of Emergency Physicians open · 2020Review
- Post-hypoxic myoclonus: The good, the bad and the ugly.Clinical neurophysiology practice · 2017Article
- Myoclonus After Cardiac Arrest: Where Do We Go From Here?Epilepsy currentsArticle
- Presumptive Acute Post-Hypoxic Myoclonus Following Return of Spontaneous Circulation in a Cat and a Dog.Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)Article
- Trismus as a Presenting Symptom in a Case of Progressive Encephalopathy with Rigidity and Myoclonus.Case reports in neurologyArticle
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neurological function following cardiac arrest often determines prognosis. Objective tests, including formal neurological examination and neurophysiological testing, are performed to provide medical providers and decision-makers information to help guide care based on the extent of neurologic injury. The demonstration of post-hypoxic myoclonus on examination has been described to portend poor outcome after cardiac arrest, but recent studies have challenged this idea given that different forms of post-hypoxic myoclonus predict disparate prognoses. The presence of myoclonus status epilepticus (MSE) usually signals a poor outcome, especially if generalized. Lance-Adams syndrome (LAS), another form of post-hypoxic myoclonus, carries a better prognosis. Differentiating subtypes of post-hypoxic myoclonus is therefore critical. This can be difficult in the acute setting with clinical examination alone due to the use of sedation to facilitate mechanical ventilation, and neurophysiological studies may be more reliable. In this review, we describe and compare clinical and neurophysiological features of MSE and LAS. Generalized epileptiform activity and burst suppression on electroencephalography tend to be more common in MSE, and focal epileptiform activity at the vertex may define LAS. Those with multifocal MSE may have better outcomes than those with generalized MSE. We conclude that neurophysiological testing is vital acutely after cardiac arrest when post-hypoxic myoclonus is present to help determine prognostication and guide decision-making.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.