Evidence map›Paper›PMID 30214959›Full record

ArticleClinical neurophysiology practice2016

Electrochemical skin conductance for quantitative assessment of sweat function: Normative values in children.

Laurène Leclair-Visonneau, Tristan Bosquet, Armelle Magot, Guillemette Fayet, Christèle Gras-Le Guen, Antoine Hamel, Yann Péréon

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Clinical neurophysiology practice, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04262778 (Diagnostic Accuracy of Electrochemical Skin Conductance Measurement in Paediatric Small Fibre Neuropathy Following Neurotoxic Chemotherapy), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04262778 completednot on this mapstarted 2020, after this paper: background citation

Diagnostic Accuracy of Electrochemical Skin Conductance Measurement in Paediatric Small Fibre Neuropathy Following Neurotoxic Chemotherapy

TypeobservationalSponsorAssistance Publique - Hôpitaux de ParisRan2020 to 2023Enrolled55ConditionsChemotherapy-induced Peripheral NeuropathyArmselectrochemical skin conductance measurement
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Cardiovascular autonomic dysfunction and sleep abnormalities in children with Prader-Willi syndrome.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2025
    Article
  3. Article
  4. Review
  5. Review
  6. Association of electrochemical skin conductance with neuropathy in chemotherapy-treated patients.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022
    Article
  7. Acute monophasic erythromelalgia pain in five children diagnosed as small-fiber neuropathy.European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2020
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Laurène Leclair-VisonneauCHU Nantes, Laboratoire d'Explorations Fonctionnelles, Hôtel-Dieu, Nantes, France.
Tristan BosquetCHU Nantes, Laboratoire d'Explorations Fonctionnelles, Hôtel-Dieu, Nantes, France.
Armelle MagotCHU Nantes, Laboratoire d'Explorations Fonctionnelles, Hôtel-Dieu, Nantes, France.
Guillemette FayetCHU Nantes, Laboratoire d'Explorations Fonctionnelles, Hôtel-Dieu, Nantes, France.
Christèle Gras-Le GuenCHU Nantes, Clinique Médicale Pédiatrique, Hôpital Mère-Enfant, Nantes, France.
Antoine HamelCHU Nantes, Chirurgie Infantile, Hôpital Mère-Enfant, Nantes, France.
Yann PéréonCHU Nantes, Laboratoire d'Explorations Fonctionnelles, Hôtel-Dieu, Nantes, France.
Centre d'Investigation Clinique de Nantes · FRHôpital Mère-Enfant · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe Sudoscan™ system (Impeto Medical, Paris, France) has been recently proposed as a standardized, easy, painless tool for sudomotor function assessment. It is now used as an additional diagnostic tool in small fibre neuropathy. So far, no work has been published in children. The aim of this study was to measure electrochemical skin conductance (ESC) using the Sudoscan™ system in children in order to assess its feasibility and to provide normative values.

methods100 children were included in the study: 55 girls and 45 boys, age rank 2-17, mean 10.5 y. They were accompanying their brother or sister who came as outclinic patients in the Department of Paediatrics or the Department of Paediatric surgery of the University Hospital.

resultsAll subjects underwent the test. It was performed without any difficulty, except for some of the youngest who sometimes had some trouble in keeping calm for 3 min over the plates. 4 subjects who took the test were excluded from the analysis (2 diabetic patients and 2 having had previous chemotherapy). ESC was quite stable along childhood with an overall 80.1 μS value for hands and 81.9 μS for feet, very similar to what is observed in adults.

conclusionMaturation process seems to occur early in life, in accordance to sudomotor control when assessed by sympathetic skin response, which is also recorded early in infancy. SIGNIFICANCE: ESC measurement is a simple and easy-to-perform test that can be performed in the clinical setting in children in 5 min.

Indexed as

Autonomic nerve systemChildrenSudation assessment

Identifiers

PMID30214959
PMCPMC6123897
OpenAlexW2506939215

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.