ArticleInternational journal of retina and vitreous2018
Change in subfoveal choroidal thickness in diabetes and in various grades of diabetic retinopathy.
Article in International journal of retina and vitreous, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 31 citations in OpenAlex.
- Assessing acute nicotine impact on choroidal thickness: a randomized, double-blinded study comparing smoking cessation aids, including nicotine gum and electronic cigarettes.International ophthalmology · 2024Trial
- Article
- Three-Dimensional Choroidal Vessels Assessment in Diabetic Retinopathy.Investigative ophthalmology & visual science · 2025Article
- Relationship between age and subfoveal choroidal thickness and its clinical implications.World journal of diabetes · 2024Article
- Subfoveal choroidal thickness in a general elderly population; Tehran geriatric eye study.BMC ophthalmology · 2024Article
- Vascular changes of the choroid and their correlations with visual acuity in diabetic retinopathy.Frontiers in endocrinology · 2024Article
- Alterations in the Choroidal Sublayers in Relationship to Severity and Progression of Diabetic Retinopathy: A Swept-Source OCT Study.Ophthalmology science · 2022Article
- Macular Choroidal Thickness and the Risk of Referable Diabetic Retinopathy in Type 2 Diabetes: A 2-Year Longitudinal Study.Investigative ophthalmology & visual science · 2022Article
- Reversed Neurovascular Coupling on Optical Coherence Tomography Angiography Is the Earliest Detectable Abnormality before Clinical Diabetic Retinopathy.Journal of clinical medicine · 2020Article
- Choroidal Thickness in Diabetes and Diabetic Retinopathy: A Swept Source OCT Study.Investigative ophthalmology & visual science · 2020Article
- Ocular surface heat flux density as a biomarker related to diabetic retinopathy (pilot study).Advances in ophthalmology practice and researchArticle
- Evaluation of Choroidal Thickness in Type 2 Diabetes Using Spectral-Domain Optical Coherence Tomography.Romanian journal of ophthalmologyObservational
- Comparison of choroidal thickness in eyes of diabetic patients with eyes of healthy individuals using optical coherence tomography in a tertiary care hospital.Pakistan journal of medical sciencesArticle
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo evaluate subfoveal choroidal thickness (SFCT) change in diabetes and in various grades of diabetic retinopathy (DR) in comparison to age-matched healthy subjects.
methodsThis prospective observational study included 100 eyes of diabetic patients without DR (group D), 100 eyes with DR (group R), and 100 eyes of healthy subjects (group N). The assessment included demographics, duration of diabetes, comprehensive ocular examination, fundus photography with/without fundus fluorescein angiography, spectral domain optical coherence tomography with enhanced depth imaging to assess SFCT.
resultsThe SFCT was comparable between groups N (310.65 ± 37.34 µm) and D (308.48 ± 30.06 µm; P = 0.60), but was significantly lower in R (296.52 ± 21.41 µm; P < 0.01). The SFCT was significantly lower in proliferative DR (n = 36; SFCT = 284.56 ± 21.09 µm) as compared to non-proliferative DR (n = 64; SFCT = 303.25 ± 18.59 µm; P < 0.001). The SFCT had moderately negative correlation with severity of DR (R = - 0.50; P < 0.01). The difference in SFCT when compared with normal subjects was significant only in severe/very severe non-proliferative DR (294.47 ± 15.65 µm; P < 0.01) and in proliferative DR (284.56 ± 21.09 µm; P < 0.01). There was a negative correlation of SFCT with the duration of diabetes (R = - 0.41; P < 0.01).
conclusionSFCT decreases with increasing duration of diabetes. The decrease is significant after the onset of severe DR, and is proportionate to the severity of DR.
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