Evidence map›Paper›PMID 30214756›Full record

ArticleClinical case reports2018

Identification of a BRCA2 mutation in a Turkish family with early-onset breast cancer.

Elifnaz Celik, Kubra Ermis Tekkus, Izzet Mehmet Akcay, Gizem Alkurt Sal, Fikret Ezberci, Gizem Dinler Doganay, Levent Doganay

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Elifnaz CelikDepartment of Molecular Biology-Genetics & Biotechnology Istanbul Technical University Istanbul Turkey.ORCID 0000-0002-0324-5228
Kubra Ermis TekkusGLAB (Genomic Laboratory) Istanbul Association of Northern Anatolian Public Hospitals Istanbul Turkey.
Izzet Mehmet AkcayDepartment of Molecular Biology-Genetics & Biotechnology Istanbul Technical University Istanbul Turkey.
Gizem Alkurt SalDepartment of Molecular Biology-Genetics & Biotechnology Istanbul Technical University Istanbul Turkey.
Fikret EzberciGLAB (Genomic Laboratory) Istanbul Association of Northern Anatolian Public Hospitals Istanbul Turkey.
Gizem Dinler DoganayDepartment of Molecular Biology-Genetics & Biotechnology Istanbul Technical University Istanbul Turkey.
Levent DoganayGLAB (Genomic Laboratory) Istanbul Association of Northern Anatolian Public Hospitals Istanbul Turkey.
Istanbul Eye Hospital · TRÜmraniye Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We used a multi-gene panel testing to identify the germline variants in a mother-daughter pair with early-onset breast cancer, and detected one pathogenic protein-truncating variant in

Indexed as

ATMBRCA1/2early‐onset breast cancergeneticsmulti‐gene panel testingoncology

Identifiers

PMID30214756
PMCPMC6132100
OpenAlexW2883876353

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.