Evidence map›Paper›PMID 30214714›Full record

ArticleClinical and translational allergy2018

Calu-3 epithelial cells exhibit different immune and epithelial barrier responses from freshly isolated primary nasal epithelial cells in vitro.

Katleen Martens, Peter W Hellings, Brecht Steelant

Open access · goldAbstract read
In one paragraph

Article in Clinical and translational allergy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Exploring the Role ofACS infectious diseases · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Nanomaterials (Basel, Switzerland) · 2021
    Article
  6. Article
  7. Article
  8. Article
  9. Epithelial barriers in allergy and asthma.The Journal of allergy and clinical immunology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Katleen Martens1Department of Microbiology and Immunology, Laboratory of Clinical Immunology, KU Leuven, Herestraat 49, Box 811, 3000 Louvain, Belgium.ORCID 0000-0002-8741-8252
Peter W Hellings1Department of Microbiology and Immunology, Laboratory of Clinical Immunology, KU Leuven, Herestraat 49, Box 811, 3000 Louvain, Belgium.ORCID 0000-0001-6898-688X
Brecht Steelant1Department of Microbiology and Immunology, Laboratory of Clinical Immunology, KU Leuven, Herestraat 49, Box 811, 3000 Louvain, Belgium.ORCID 0000-0002-0358-9362
KU Leuven · BEAmsterdam UMC Location University of Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epithelial cell lines are often used to evaluate the effect of exogenous/endogenous stimuli on epithelial barrier function and innate immune responses in allergic airway diseases, without clear view on differences between epithelial cell lines and primary nasal epithelial cell responses. In this observational study, we compared the response of Calu-3 and primary nasal epithelial cells to two relevant exogenous stimuli: i.e.

Indexed as

Calu-3 epithelial cell lineHouse dust mite extractPrimary nasal epithelial cellsStaphylococcus aureus enterotoxin BTrans-epithelial electrical resistance

Identifiers

PMID30214714
PMCPMC6134498
OpenAlexW2889616542

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.